Evidence map›Paper›PMID 37996651›Full record

ArticleScientific reports2023

Comparison between vision transformers and convolutional neural networks to predict non-small lung cancer recurrence.

Annarita Fanizzi, Federico Fadda, Maria Colomba Comes, Samantha Bove, Annamaria Catino, Erika Di Benedetto, Angelo Milella, Michele Montrone, Annalisa Nardone, Clara Soranno and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Annarita Fanizzi *Struttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Federico Fadda *Struttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Maria Colomba Comes *Struttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy. m.c.comes@oncologico.bari.it.
Samantha BoveStruttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy. s.bove@oncologico.bari.it.
Annamaria CatinoUnità Operativa Complessa di Oncologia Toracica, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Erika Di BenedettoUnità Operativa Complessa di Oncologia Medica, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Angelo MilellaDipartimento di ElettronicaInformazione e Bioingegneria, Politecnico di Milano, Via Giuseppe Ponzio, 34, 20133, Milan, Italy.
Michele MontroneUnità Operativa Complessa di Oncologia Toracica, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Annalisa NardoneUnità Operativa Complessa di Radioterapia, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Clara SorannoStruttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Alessandro RizzoUnità Operativa Complessa di Oncologia Medica 'Don Tonino Bello', I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Deniz Can GuvenDepartment of Medical Oncology, Hacettepe University Cancer Institute, 06100, Sihhiye, Ankara, Turkey.
Domenico GalettaUnità Operativa Complessa di Oncologia Toracica, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Raffaella MassafraStruttura Semplice Dipartimentale Fisica Sanitaria, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy.
Istituto Tumori Bari · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITHacettepe University Hospital · TRPolitecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Small cell lung cancer (NSCLC) is one of the most dangerous cancers, with 85% of all new lung cancer diagnoses and a 30-55% of recurrence rate after surgery. Thus, an accurate prediction of recurrence risk in NSCLC patients during diagnosis could be essential to drive targeted therapies preventing either overtreatment or undertreatment of cancer patients. The radiomic analysis of CT images has already shown great potential in solving this task; specifically, Convolutional Neural Networks (CNNs) have already been proposed providing good performances. Recently, Vision Transformers (ViTs) have been introduced, reaching comparable and even better performances than traditional CNNs in image classification. The aim of the proposed paper was to compare the performances of different state-of-the-art deep learning algorithms to predict cancer recurrence in NSCLC patients. In this work, using a public database of 144 patients, we implemented a transfer learning approach, involving different Transformers architectures like pre-trained ViTs, pre-trained Pyramid Vision Transformers, and pre-trained Swin Transformers to predict the recurrence of NSCLC patients from CT images, comparing their performances with state-of-the-art CNNs. Although, the best performances in this study are reached via CNNs with AUC, Accuracy, Sensitivity, Specificity, and Precision equal to 0.91, 0.89, 0.85, 0.90, and 0.78, respectively, Transformer architectures reach comparable ones with AUC, Accuracy, Sensitivity, Specificity, and Precision equal to 0.90, 0.86, 0.81, 0.89, and 0.75, respectively. Based on our preliminary experimental results, it appears that Transformers architectures do not add improvements in terms of predictive performance to the addressed problem.

Indexed as

Carcinoma, Non-Small-Cell LungDeep LearningLung NeoplasmsHumansNeoplasm Recurrence, LocalNeural Networks, Computer

Identifiers

PMID37996651
PMCPMC10667245
OpenAlexW4388946866

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.