Evidence map›Paper›PMID 37996708›Full record

ReviewNature microbiology2023

Metabolic exchanges are ubiquitous in natural microbial communities.

Christian Kost, Kiran Raosaheb Patil, Jonathan Friedman, Sarahi L Garcia, Markus Ralser

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Virulence · 2026
    Article
  3. Cross-feeding enables robust coexistence between four bacterial species.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian KostOsnabrück University, Department of Ecology, School of Biology/Chemistry, Osnabrück, Germany. christiankost@gmail.com.ORCID 0000-0002-7870-7343
Kiran Raosaheb PatilMedical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK. kp533@cam.ac.uk.ORCID 0000-0002-6166-8640
Jonathan FriedmanDepartment of Plant Pathology and Microbiology, The Hebrew University of Jerusalem, Rehovot, Israel. yonatan.friedman@mail.huji.ac.il.ORCID 0000-0001-8476-8030
Sarahi L GarciaDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Stockholm, Sweden. sarahi.garcia@su.se.ORCID 0000-0002-8622-0308
Markus RalserCharité - Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany. markus.ralser@charite.de.ORCID 0000-0001-9535-7413

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) KO 3909/2-1Deutsche Forschungsgemeinschaft (German Research Foundation) KO 3909/4-1Deutsche Forschungsgemeinschaft (German Research Foundation) KO 3909/6-1Deutsche Forschungsgemeinschaft (German Research Foundation) KO 3909/9-1EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 866028EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) ERC-SyG-2020 951475Israel Science Foundation (ISF) 883/22Vetenskapsrådet (Swedish Research Council) 2022-03077Volkswagen Foundation (VolkswagenStiftung) 9B831Wellcome Trust (Wellcome) IA 200829/Z/16/Z
6 · The paper itself

Abstract

Microbial communities drive global biogeochemical cycles and shape the health of plants and animals-including humans. Their structure and function are determined by ecological and environmental interactions that govern the assembly, stability and evolution of microbial communities. A widely held view is that antagonistic interactions such as competition predominate in microbial communities and are ecologically more important than synergistic interactions-for example, mutualism or commensalism. Over the past decade, however, a more nuanced picture has emerged, wherein bacteria, archaea and fungi exist within interactive networks in which they exchange essential and non-essential metabolites. These metabolic interactions profoundly impact not only the physiology, ecology and evolution of the strains involved, but are also central to the functioning of many, if not all, microbiomes. Therefore, we advocate for a balanced view of microbiome ecology that encompasses both synergistic and antagonistic interactions as key forces driving the structure and dynamics within microbial communities.

Indexed as

MicrobiotaAnimalsArchaeaBacteriaHumansSymbiosis

Identifiers

PMID37996708

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.