Evidence map›Paper›PMID 37999480›Full record

ArticleVeterinary sciences2023

Intestine Health and Barrier Function in Fattening Rabbits Fed Bovine Colostrum.

Lucia Aidos, Margherita Pallaoro, Giorgio Mirra, Valentina Serra, Marta Castrica, Stella Agradi, Giulio Curone, Daniele Vigo, Federica Riva, Claudia Maria Balzaretti and 5 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lucia AidosDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.
Margherita PallaoroDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-8292-4543
Giorgio MirraDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.
Valentina SerraDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-2686-075X
Marta CastricaDipartimento di Biomedicina Comparata e Alimentazione-BCA, University of Padua, Viale dell'Università, 16, 35020 Legnaro, Italy.
Stella AgradiDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0003-4649-1151
Giulio CuroneDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-6352-0036
Daniele VigoDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-6292-4992
Federica RivaDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-1270-1627
Claudia Maria BalzarettiDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-0309-3260
Roberta De BellisDepartment of Biomolecular Sciences, University of Urbino "Carlo Bo", Via A. Saffi 2, 61029 Urbino, Italy.
Grazia PastorelliDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-7666-2663
Gabriele BrecchiaDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0003-4750-2801
Silvia Clotilde ModinaDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-2780-5971
Alessia Di GiancamilloDepartment of Biomedical Sciences for Health, University of Milan, Via Mangiagalli 31, 20133 Milan, Italy.ORCID 0000-0003-1674-3020

Funding

University of Milan 0
6 · The paper itself

Abstract

The permeability of the immature intestine is higher in newborns than in adults; a damaged gut barrier in young animals increases the susceptibility to digestive and infectious diseases later in life. It is therefore of major importance to avoid impairment of the intestinal barrier, specifically in a delicate phase of development, such as weaning. This study aimed to evaluate the effects of bovine colostrum supplementation on the intestinal barrier, such as the intestinal morphology and proliferation level and tight junctions expression (zonulin) and enteric nervous system (ENS) inflammation status (through the expression of PGP9.5 and GFAP) in fattening rabbits. Rabbits of 35 days of age were randomly divided into three groups (n = 13) based on the dietary administration: commercial feed (control group, CTR) and commercial feed supplemented with 2.5% and 5% bovine colostrum (BC1 and BC2 groups, respectively). Rabbits receiving the BC1 diet showed a tendency to have better duodenum morphology and higher proliferation rates (

Indexed as

bovine colostrumenteric nervous systemintestinal barrierintestinal healthrabbitszonulin

Identifiers

PMID37999480
PMCPMC10675739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.