Evidence map›Paper›PMID 38001599›Full record

ReviewCancers2023

Unveiling a Biomarker Signature of Meningioma: The Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis.

Reem Halabi, Fatima Dakroub, Mohammad Z Haider, Stuti Patel, Nayef A Amhaz, Mohammad A Reslan, Ali H Eid, Yehia Mechref, Nadine Darwiche, Firas Kobeissy and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Reem HalabiDepartment of Biological and Chemical Sciences, Lebanese International University, Beirut 1105, Lebanon.
Fatima DakroubDepartment of Experimental Pathology, Microbiology and Immunology and Center for Infectious Diseases Research, Faculty of Medicine, American University of Beirut, Beirut 1107, Lebanon.ORCID 0000-0002-7432-0977
Mohammad Z HaiderDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-0598-5171
Stuti PatelDepartment of Biology, University of Florida, Gainesville, FL 32601, USA.ORCID 0009-0001-2375-9509
Nayef A AmhazDepartment of Biology, University of Florida, Gainesville, FL 32601, USA.
Mohammad A ReslanDepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107, Lebanon.ORCID 0000-0001-8010-3269
Ali H EidDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3004-5675
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-6661-6073
Nadine DarwicheDepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107, Lebanon.ORCID 0000-0002-1862-5426
Firas KobeissyDepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107, Lebanon.ORCID 0000-0002-5008-6944
Ibrahim OmeisHammoud Hospital University Medical Center, Saida 652, Lebanon.
Abdullah A ShaitoBiomedical Research Center, College of Medicine, and Department of Biomedical Sciences at College of Health Sciences, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3524-7962
American University of Beirut · LBQatar University · QAUniversity of Florida · USLancaster General Hospital · USLebanese International University · LBMorehouse School of Medicine · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation into advanced grades classified by World Health Organization (WHO) into Grades 1 to 3. Meningiomas' tremendous variability in tumor behavior and slow growth rates complicate their diagnosis and treatment. A deeper comprehension of the molecular pathways and cellular microenvironment factors implicated in meningioma survival and pathology is needed. This review summarizes the known genetic and epigenetic aberrations involved in meningiomas, with a focus on neurofibromatosis type 2 (

Indexed as

biomarkermeningiomamiRNANF2 mutationsproteomics

Identifiers

PMID38001599
PMCPMC10670806
OpenAlexW4388540359

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.