Evidence map›Paper›PMID 38002199›Full record

ArticleFoods (Basel, Switzerland)2023

Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies.

Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang, Jun Zhang

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Solvent-Dependent Phenolic Profiling and Bioactivities ofMolecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kumaravel KaliaperumalNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.ORCID 0000-0003-2603-6733
Linyan ZhangNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.
Liangliang GaoNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.
Qin XiongNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.
Yan LiangNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.
Yueming JiangNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.ORCID 0000-0002-4648-9572
Jun ZhangNational Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou 341003, China.ORCID 0000-0002-5002-9827
Gannan Normal University · CNChinese Academy of Sciences · CN

Funding

Key Research Project of Jiangxi Province 20224BBF61026Key Research Project of Jiangxi Province 2023lzdf03071the "Double Thousand Talents Plan" of Jiangxi Province jxsq2019102029
6 · The paper itself

Abstract

The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties. This paper evaluates the effects of hesperidin on α-glucosidase through inhibitory kinetics, fluorescence quenching, and molecular docking methods for the first time. The inhibition kinetic analysis shows that hesperidin reversibly inhibited the α-glucosidase activity with an IC

Indexed as

antidiabeticflavonoidhesperidinorangeα-glucosidase

Identifiers

PMID38002199
PMCPMC10670601
OpenAlexW4388724580

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.