Evidence map›Paper›PMID 38002597›Full record

ArticleJournal of clinical medicine2023

18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Findings of Polymyalgia Rheumatica in Patients with Giant Cell Arteritis.

Elena Heras-Recuero, Marta Martínez de Bourio-Allona, Laura Cristina Landaeta-Kancev, Teresa Blázquez-Sánchez, Arantxa Torres-Roselló, Miguel Álvarez-Rubio, Mariam Belhaj-Gandar, Juan Antonio Martínez-López, Luis Martínez-Dhier, Javier Llorca and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Role and potential ofFrontiers in medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Elena Heras-RecueroDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.
Marta Martínez de Bourio-AllonaDepartment of Nuclear Medicine, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Laura Cristina Landaeta-KancevDepartment of Nuclear Medicine, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Teresa Blázquez-SánchezDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.
Arantxa Torres-RosellóDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.
Miguel Álvarez-RubioDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.
Mariam Belhaj-GandarDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.
Juan Antonio Martínez-LópezDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-8199-8631
Luis Martínez-DhierDepartment of Nuclear Medicine, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Javier LlorcaCIBER Epidemiología y Salud Pública (CIBERESP), Department of Medical and Surgical Sciences, University of Cantabria, 39011 Santander, Spain.
Raquel LargoDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-6525-2944
Miguel Ángel González-GayDivision of Rheumatology, ISS-Jiménez Díaz Foundation University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-7924-7406
Hospital Universitario Fundación Jiménez Díaz · ESUniversidad de Cantabria · ES

Funding

Instituto de Salud Carlos III (Spain) FIS PI22/01263 and RICORS RD21/0002/0025
6 · The paper itself

Abstract

objectiveGiant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are often overlapping conditions. We studied whether 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is useful in identifying PMR in the setting of large vessel (LV) GCA.

methodsLV-GCA patients diagnosed by PET-CT at a tertiary care center for a population of 450,000 people over a two-year period were reviewed. Scoring was performed based on potential significant FDG uptake at up to 16 sites in nine different extravascular areas (SCORE 16). Differences in extravascular sites of significant FDG uptake were evaluated between LV-GCA with a clinical diagnosis of PMR or not.

resultsFifty-four patients were diagnosed with LV-GCA by 18F-FDG-PET-CT. Of them, 21 (38.8%) were clinically diagnosed with PMR. Significant extravascular FDG uptake was more frequently observed in those with a clinical diagnosis of PMR. In this sense, the SCORE 16 was higher in those with clinical PMR (5.10 ± 4.05 versus 1.73 ± 2.31 in those without a clinical diagnosis of PMR;

conclusionsSignificant extravascular 18F-FDG-PET-CT uptake may help establish a clinical diagnosis of PMR in patients with LV-GCA. These patients are more commonly diagnosed with PMR if they have significant FDG uptake in the shoulder, greater trochanter, and lumbar interspinous areas.

Indexed as

FDG uptakegiant cell arteritislarge vessel vasculitispolymyalgia rheumaticapositron emission tomography–computed tomography (PET-CT) with 18F-fluorodeoxyglucose (FDG)

Identifiers

PMID38002597
PMCPMC10672295
OpenAlexW4388500130

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.