Evidence map›Paper›PMID 38003113›Full record

ArticleAnimals : an open access journal from MDPI2023

RNAseq Analysis of Livers from Pigs Treated with Testosterone and Nandrolone Esters: Selection and Field Validation of Transcriptional Biomarkers.

Alessandro Benedetto, Kamil Šťastný, Nunzia Giaccio, Marianna Marturella, Elena Biasibetti, Maddalena Arigoni, Raffaele Calogero, Marilena Gili, Marzia Pezzolato, Kristína Tošnerová and 5 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Alessandro BenedettoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.ORCID 0000-0003-2173-8787
Kamil ŠťastnýDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 621 00 Brno, Czech Republic.ORCID 0000-0002-1543-291X
Nunzia GiaccioIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.
Marianna MarturellaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.
Elena BiasibettiIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.
Maddalena ArigoniDipartimento di Biotecnologie e Scienze della Salute, Core-Lab di Bioinformatica e Genomica, Università degli Studi di Torino, 10124 Turin, Italy.
Raffaele CalogeroDipartimento di Biotecnologie e Scienze della Salute, Core-Lab di Bioinformatica e Genomica, Università degli Studi di Torino, 10124 Turin, Italy.ORCID 0000-0002-2848-628X
Marilena GiliIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.
Marzia PezzolatoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.ORCID 0000-0001-9530-9016
Kristína TošnerováDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 621 00 Brno, Czech Republic.
Nikola HodkovicováDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 621 00 Brno, Czech Republic.ORCID 0000-0003-0460-981X
Martin FaldynaDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 621 00 Brno, Czech Republic.
Roberto PuleioIstituto Zooprofilattico Sperimentale della Sicilia, 90129 Palermo, Italy.ORCID 0000-0002-3461-3353
Giancarlo BozzoDipartimento di Medicina Veterinaria, Università degli Studi di Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0002-1225-0205
Elena BozzettaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, 10154 Turin, Italy.ORCID 0000-0002-5776-738X
Istituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · ITVeterinary Research Institute · CZUniversity of Turin · ITIstituto Zooprofilattico Sperimentale Della Sicilia · ITUniversity of Bari Aldo Moro · IT

Funding

Ministero della Salute IZS PLV 03/20 RCMinistry of Agriculture QK1910311 (NAZV)
6 · The paper itself

Abstract

The use of anabolic-androgenic steroids (AASs) as growth promoters in farm animals is banned in the European Union, representing both an illicit practice and a risk for consumer health. However, these compounds are still illegally administered, often in the form of synthetic esters. This work aimed to characterize significant coding RNA perturbations related to the illicit administration of testosterone and nandrolone esters in fattening pigs. A total of 27 clinically healthy 90-day-old pigs were randomly assigned to test and control groups. Nine animals were treated with testosterone esters (Sustanon

Indexed as

fattening pigsPCAqPCRsteroid esterstranscriptomics

Identifiers

PMID38003113
PMCPMC10668810
OpenAlexW4388629241

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.