Evidence map›Paper›PMID 38003829›Full record

ArticlePathogens (Basel, Switzerland)2023

Efficacy of the Vaccine Candidate Based on the P0 Peptide against

Alina Rodríguez-Mallon, Pedro E Encinosa Guzmán, Yamil Bello, Ana Domingos, Sandra Antunes, Petr Kopacek, Ana Sofia Santos, Rita Velez, Jan Perner, Frank L Ledesma Bravo and 8 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Evolution of tick vaccinology.Parasitology · 2024
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Alina Rodríguez-MallonCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.ORCID 0000-0002-6950-6793
Pedro E Encinosa GuzmánCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.ORCID 0000-0001-9827-0364
Yamil BelloCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.
Ana DomingosGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0002-4570-2060
Sandra AntunesGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0002-5512-9093
Petr KopacekInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 České Budějovice, Czech Republic.
Ana Sofia SantosCentro de Estudos de Vetores e Doenças Infeciosas Dr. Francisco Cambournac, Instituto Nacional de Saúde Doutor Ricardo Jorge (CEVDI-INSA), 2965-575 Águas de Moura, Portugal.
Rita VelezCentro de Estudos de Vetores e Doenças Infeciosas Dr. Francisco Cambournac, Instituto Nacional de Saúde Doutor Ricardo Jorge (CEVDI-INSA), 2965-575 Águas de Moura, Portugal.
Jan PernerInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 České Budějovice, Czech Republic.ORCID 0000-0001-7719-4251
Frank L Ledesma BravoCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.
Helena FrantovaInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 České Budějovice, Czech Republic.
Jan ErhartInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 České Budějovice, Czech Republic.
Rafmary RodríguezNational Laboratory of Parasitology, Avenue San Antonio-Rincón, Km 1 1/2, Artemisa 32500, Cuba.
Alier FuentesNational Laboratory of Parasitology, Avenue San Antonio-Rincón, Km 1 1/2, Artemisa 32500, Cuba.
David DiagoCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.
Marisdania JoglarCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.
Luis MéndezNational Laboratory of Parasitology, Avenue San Antonio-Rincón, Km 1 1/2, Artemisa 32500, Cuba.
Mario Pablo EstradaCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba.ORCID 0000-0002-9776-719X
Centro de Ingeniería Genética y Biotecnología · CUInstitute of Parasitology · CZUniversidade Nova de Lisboa · PTUniversity of Lisbon · PT

Funding

Centro de Ingeniería Genética y Biotecnología Internal GrantCzech Science Foundation 20-05736Snstituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Portugal Internal GrantPrograma Iberoamericano de Ciencia y Tecnología para el Desarrollo 110RT0541
6 · The paper itself

Abstract

The control of ticks through vaccination offers a sustainable alternative to the use of chemicals that cause contamination and the selection of resistant tick strains. However, only a limited number of anti-tick vaccines have reached commercial realization. In this sense, an antigen effective against different tick species is a desirable target for developing such vaccines. A peptide derived from the tick P0 protein (pP0) conjugated to a carrier protein has been demonstrated to be effective against the

Indexed as

anti-tick vaccineP0 proteintick controlticksvaccination

Identifiers

PMID38003829
PMCPMC10675505
OpenAlexW4388760365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.