Evidence map›Paper›PMID 38009518›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia Outer-Membrane-Vesicle Vaccine.

Saugata Majumder, Shreya Das, Peng Li, Nicole Yang, Hazel Dellario, Haixin Sui, Ziqiang Guan, Wei Sun

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Biological nanoparticles from Brucella abortusJournal of nanobiotechnology · 2025
    Article
  6. Review
  7. Delivery ofmSphere · 2024
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Saugata MajumderDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Shreya DasDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Peng LiDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Nicole YangDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Hazel DellarioWadsworth Center, New York State Department of Health, Albany, NY, 12237, USA.
Haixin SuiWadsworth Center, New York State Department of Health, Albany, NY, 12237, USA.
Ziqiang GuanDepartment of Biochemistry, Duke University Medical Center, Durham, NC, 27710, USA.
Wei SunDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.ORCID 0000-0002-0071-6987

Funding

Yersinia Outer-Membrane-Vesicle Vaccines Against Pneumonic PlagueR01AI162670 · NIAID · ALBANY MEDICAL COLLEGE · PI Wei Sun · 2022 to 2026
$3.4M
Adaptive alterations of lipids in mitis group streptococciR01AI148366 · NIAID · UNIVERSITY OF TEXAS DALLAS · PI GUAN, ZIQIANG, PALMER, KELLI LEA · 2020 to 2024
$2.5M
Yersinia pseudotuberculosis-based vaccines for plague and yersiniosisR01AI125623 · NIAID · UNIVERSITY OF FLORIDA · PI SUN, WEI · 2016 to 2020
$2.3M
Intraflagellar transport process in primary cilium maintenanceR01GM143223 · NIGMS · WADSWORTH CENTER · PI SUI, HAIXIN · 2021 to 2024
$1.5M
outer Membrane Vesicle of Engineering Yersinia Pestis as a Novel Plague VaccineR21AI139703 · NIAID · ALBANY MEDICAL COLLEGE · PI SUN, WEI · 2018 to 2019
$446k
NIAID NIH HHS R01 AI125623NIAID NIH HHS R01 AI148366NIAID NIH HHS R01 AI162670NIAID NIH HHS R21 AI139703NIGMS NIH HHS R01 GM143223NIH HHS R01AI125623NIH HHS R01AI148366NIH HHS R01AI162670NIH HHS R01GM143223NIH HHS R21AI139703
6 · The paper itself

Abstract

A new Yersinia pseudotuberculosis mutant strain, YptbS46, carrying the lpxE insertion and pmrF-J deletion is constructed and shown to exclusively produce monophosphoryl lipid A (MPLA) having adjuvant properties. Outer membrane vesicles (OMVs) isolated from YptbS46 harboring an lcrV expression plasmid, pSMV13, are designated OMV

Indexed as

PlaguePlague VaccineYersinia pestisAnimalsAntigens, BacterialLipid AMiceYersiniaAntigens, BacterialLipid Amonophosphoryl lipid APlague Vaccinemonophosphoryl lipid AOUTER membrane vesiclesplague vaccineprotective immunityY. pestis

Identifiers

PMID38009518
PMCPMC11009084

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.