Evidence map›Paper›PMID 38010603›Full record

ArticleNeurochemical research2024

Hexavalent Chromium Induces Neurotoxicity by Triggering Mitochondrial Dysfunction and ROS-Mediated Signals.

Tongtong Zhang, Lina Feng, Jie Cui, Weiwei Tong, Han Zhao, Tingchao Wu, Pu Zhang, Xianjun Wang, Yingjun Gao, Jing Su and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Tongtong Zhang *Department of Neurology, People's Hospital of Linyi, Linyi, 276000, Shandong, China.
Lina Feng *Shandong Key Laboratory of TCM Multi-Target Intervention and Disease Control, The Second Affiliated Hospital of Shandong First Medical University, Taian, 271000, Shandong, China.
Jie Cui *Shandong Key Laboratory of TCM Multi-Target Intervention and Disease Control, The Second Affiliated Hospital of Shandong First Medical University, Taian, 271000, Shandong, China.
Weiwei TongDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China.
Han ZhaoDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China.
Tingchao WuDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China.
Pu ZhangDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China.
Xianjun WangDepartment of Neurology, People's Hospital of Linyi, Linyi, 276000, Shandong, China.
Yingjun GaoDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China. xp002514@126.com.
Jing SuDepartment of Cardiovascular Medicine, Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China. sujing6298464@163.com.
Xiaoyan FuShandong Key Laboratory of TCM Multi-Target Intervention and Disease Control, The Second Affiliated Hospital of Shandong First Medical University, Taian, 271000, Shandong, China. txyfu66@163.com.
Qingdao University · CNLinyi People's Hospital · CNTaian City Central Hospital · CNAffiliated Hospital of Taishan Medical University · CNSecond Affiliated Hospital of Shandong University of TCM · CNShandong First Medical University · CN

Funding

Natural Science Foundation of Shandong Province ZR2021MH089Taian City Science and Technology Development Plan 2020NS120, 2021NS139 and 2021NS295
6 · The paper itself

Abstract

Hexavalent chromium (Cr (VI)), one of the most detrimental pollutants, has been ubiquitously present in the environment and causes serious toxicity to humans, such as hepatotoxicity, nephrotoxicity, pulmonary toxicity, and cardiotoxicity. However, Cr (VI)-induced neurotoxicity in primary neuron level has not been well explored yet. Herein, potassium dichromate (K

Indexed as

Mitochondrial DiseasesOxidative StressAnimalsChromiumGlutathioneHumansProto-Oncogene Proteins c-bcl-2RatsReactive Oxygen SpeciesChromiumchromium hexavalent ionGlutathioneProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesBcl-2 familyDNA damageHexavalent chromiumMitochondrial dysfunctionNeurotoxicityReactive oxygen species

Identifiers

PMID38010603
OpenAlexW4389050207

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.