Evidence map›Paper›PMID 38012168›Full record

ArticleScientific reports2023

Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction.

Shu-Yu Tang, Hsi-Pin Ma, Chen Lin, Men-Tzung Lo, Lian-Yu Lin, Tsung-Yan Chen, Cho-Kai Wu, Jiun-Yang Chiang, Jen-Kuang Lee, Chi-Sheng Hung and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shu-Yu TangDepartment of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Hsi-Pin MaDepartment of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Chen LinDepartment of Biomedical Sciences and Engineering, National Central University, No. 300, Zhongda Road, Taoyuan, Taiwan. clin@ncu.edu.tw.
Men-Tzung LoDepartment of Biomedical Sciences and Engineering, National Central University, No. 300, Zhongda Road, Taoyuan, Taiwan.
Lian-Yu LinDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Tsung-Yan ChenDepartment of Internal Medicine, National Taiwan University Hospital Hsinchu Branch, Hsinchu, Taiwan.
Cho-Kai WuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Jiun-Yang ChiangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Jen-Kuang LeeDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chi-Sheng HungDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Li-Yu Daisy LiuDepartment of Agronomy, Biometry Division, National Taiwan University, Taipei, Taiwan.
Yu-Wei ChiuDepartment of Computer Science and Engineering, Yuan Ze university, Taoyuan, Taiwan.
Cheng-Hsuan TsaiDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. chenghsuan.richard.tsai@gmail.com.
Yen-Tin LinDepartment of Internal Medicine, Taoyuan General Hospital, Taoyuan, Taiwan. Iantin008@gmail.com.
Chung-Kang PengDivision of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, USA.
Yen-Hung LinDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

Department of Health, Executive, R.O.C. PTH 109-13Department of Health, Executive Yuan, R.O.C. PTH 110-29Ministry of Science and Technology, Taiwan 110-2314-B-002-134-MY3National Taiwan University Hospital Yunlin Branch 110-N012
6 · The paper itself

Abstract

Heart rhythm complexity (HRC), a subtype of heart rate variability (HRV), is an important tool to investigate cardiovascular disease. In this study, we aimed to analyze serial changes in HRV and HRC metrics in patients with inferior ST-elevation myocardial infarction (STEMI) within 1 year postinfarct and explore the association between HRC and postinfarct left ventricular (LV) systolic impairment. We prospectively enrolled 33 inferior STEMI patients and 74 control subjects and analyzed traditional linear HRV and HRC metrics in both groups, including detrended fluctuation analysis (DFA) and multiscale entropy (MSE). We also analyzed follow-up postinfarct echocardiography for 1 year. The STEMI group had significantly lower standard deviation of RR interval (SDNN), and DFAα2 within 7 days postinfarct (acute stage) comparing to control subjects. LF power was consistently higher in STEMI group during follow up. The MSE scale 5 was higher at acute stage comparing to control subjects and had a trend of decrease during 1-year postinfarct. The MSE area under scale 1-5 showed persistently lower than control subjects and progressively decreased during 1-year postinfarct. To predict long-term postinfarct LV systolic impairment, the slope between MSE scale 1 to 5 (slope 1-5) had the best predictive value. MSE slope 1-5 also increased the predictive ability of the linear HRV metrics in both the net reclassification index and integrated discrimination index models. In conclusion, HRC and LV contractility decreased 1 year postinfarct in inferior STEMI patients, and MSE slope 1-5 was a good predictor of postinfarct LV systolic impairment.

Indexed as

ST Elevation Myocardial InfarctionCardiovascular Physiological PhenomenaEchocardiographyHeart RateHumansVentricular Function, Left

Identifiers

PMID38012168
PMCPMC10681979

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.