Evidence map›Paper›PMID 38012403›Full record

ArticleNature cell biology2023

Leptin receptor

Xiang Gao, Malea M Murphy, James G Peyer, Yuehan Ni, Min Yang, Yixuan Zhang, Jiaming Guo, Nergis Kara, Claire Embree, Alpaslan Tasdogan and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Nature cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Bridging skeletal stem cell diversity and human skeletal modeling.Journal of bone and mineral metabolism · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Single-cell sequencing uncovers sensory neuron-mediated CGRP signaling as a driver of sarcoma progression.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. The Sympathetic Nervous Influence on Hematopoiesis Up To Date.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Deep imaging of LepRBone research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Xiang GaoNational Institute of Biological Sciences, Beijing, China.
Malea M MurphyChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-7071-6862
James G PeyerChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yuehan NiNational Institute of Biological Sciences, Beijing, China.
Min YangNational Institute of Biological Sciences, Beijing, China.
Yixuan ZhangNational Institute of Biological Sciences, Beijing, China.
Jiaming GuoNational Institute of Biological Sciences, Beijing, China.
Nergis KaraChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Claire EmbreeChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alpaslan TasdoganChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jessalyn M UbellackerChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-7855-9125
Genevieve M CraneRobert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0001-9274-0214
Shentong FangSchool of Biopharmacy, China Pharmaceutical University, Nanjing, China.ORCID 0000-0002-3520-7007
Zhiyu ZhaoChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-6308-6997
Bo ShenNational Institute of Biological Sciences, Beijing, China. ShenBo@nibs.ac.cn.ORCID 0000-0002-5237-6144
Sean J MorrisonChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Sean.Morrison@UTSouthwestern.edu.ORCID 0000-0003-1587-8329
The University of Texas Southwestern Medical Center · USBeijing Normal University · CNNational Institute of Biological Sciences, Beijing · CNPeking University · CNCambrian Innovation (United States) · USChina Pharmaceutical University · CNCleveland Clinic · USEssen University Hospital · DEHarvard University · USSouthwestern Medical Center · USTexas A&M University System · US

Funding

UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
The Metabolic Regulation of Hematopoietic Stem Cell FunctionR01DK118745 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MORRISON, SEAN J · 2019 to 2023
$1.8M
The metabolic regulation of hematopoietic stem cell functionR56DK118745 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MORRISON, SEAN J · 2018 to 2018
$100k
NIDDK NIH HHS P30 DK127984NIDDK NIH HHS R01 DK118745NIDDK NIH HHS R56 DK118745
6 · The paper itself

Abstract

The bone marrow contains peripheral nerves that promote haematopoietic regeneration after irradiation or chemotherapy (myeloablation), but little is known about how this is regulated. Here we found that nerve growth factor (NGF) produced by leptin receptor-expressing (LepR

Indexed as

Bone MarrowReceptors, LeptinBone Marrow CellsHematopoietic Stem CellsNerve Growth FactorNerve RegenerationNerve Growth FactorReceptors, Leptin

Identifiers

PMID38012403
PMCPMC10709146
OpenAlexW4389045816

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.