Evidence map›Paper›PMID 38018182›Full record

ReviewInfectious disorders drug targets2024

The Re-emergence of Diphtheria Amidst Multiple Outbreaks in Nigeria.

Pius Omoruyi Omosigho, Okesanya Olalekan John, Olaniyi Abideen Adigun, Hakeem Kayode Hassan, Olaleke Noah Olabode, Abioye Sunday Micheal, Usman Abubakar Haruna, Amandeep Singh, Emery Manirambona

Abstract readReviewHistorical Article
PubMed Publisher
In one paragraph

Review in Infectious disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Serological evaluation of immunity againstHuman vaccines & immunotherapeutics · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

Pius Omoruyi OmosighoDepartment of Medical Laboratory Science, Edo State University Uzairue, Benin, Nigeria.ORCID 0000-0002-8431-3033
Okesanya Olalekan JohnDepartment of Medical Laboratory Science, Neuropsychiatric Hospital, Aro, Abeokuta, Nigeria.ORCID 0000-0002-3809-4271
Olaniyi Abideen AdigunKwara State University, Malete, Ilorin, Kwara State, Nigeria.ORCID 0000-0002-2375-6375
Hakeem Kayode HassanKwara State University, Malete, Ilorin, Kwara State, Nigeria.ORCID 0000-0002-8508-3006
Olaleke Noah OlabodeObafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State, Nigeria.ORCID 0000-0001-7070-276X
Abioye Sunday MichealDepartment of Public Health, Faculty of Basic Medical Sciences, Adeleke University, Ede, Osun State, Nigeria.ORCID 0000-0002-8916-2350
Usman Abubakar HarunaNazarbayev University School of Medicine, Astana, Kazakhstan.ORCID 0000-0002-9135-0473
Amandeep SinghDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.ORCID 0000-0003-1994-1487
Emery ManirambonaCollege of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.ORCID 0000-0002-0579-3607
Kwara State University · NGAdeleke University · NGAmbrose Alli University · NGFederal Neuro Psychiatric Hospital · NGIndo Soviet Friendship College of Pharmacy · INNazarbayev University · KZObafemi Awolowo University Teaching Hospitals Complex · NGUniversity of Rwanda · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diphtheria, a vaccine-preventable disease, has resurfaced in Nigeria, where many outbreaks have been reported in recent years. The outbreaks have occurred across the country, including in areas with high vaccination coverage. Corynebacterium diphtheriae, the causal agent, is a highly contagious bacteria that can cause severe respiratory and systemic symptoms and can be fatal if not treated. The reemergence of diphtheria in Nigeria is most likely due to a combination of factors, including gaps in routine immunization regimens. The outbreak is further aggravated by multiple epidemics, which have diverted resources and attention away from the emergency of other infectious diseases. Furthermore, there is a lack of awareness of diphtheria in Nigeria. With a focus on the difficulties in controlling the disease, methods of diagnosis, available treatments, and preventive measures, this study provides a thorough analysis of diphtheria, covering its historical context, clinical presentation, associated complications, and current outbreaks. It emphasizes how important vaccination, early detection, and better access to healthcare are in reducing diphtheria outbreaks. The study highlights the serious effects of diphtheria on public health, particularly in regions with scarce resources and vaccine resistance, and offers a number of suggestions to overcome these challenges and prevent further outbreaks.

Indexed as

Corynebacterium diphtheriaeDiphtheriaDisease OutbreaksCommunicable Diseases, EmergingHistory, 21st CenturyHumansNigeriaPublic HealthVaccinationbacterial infectionCorynebacterium diphtheriaeDiphtheriadiphtheria toxinoutbreakreemergence.

Identifiers

PMID38018182
OpenAlexW4389148867

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.