Evidence map›Paper›PMID 38019311›Full record

ArticleActa neuropathologica2023

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Jeffrey D Rothstein, Victoria Baskerville, Sampath Rapuri, Emma Mehlhop, Paymaan Jafar-Nejad, Frank Rigo, Frank Bennett, Sarah Mizielinska, Adrian Isaacs, Alyssa N Coyne

Open access · greenAbstract read
In one paragraph

Article in Acta neuropathologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Generation of Donor-Specific iPSC for Modelling Lysosomal Storage Disorders.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. CTAD taskforce: genetic therapies in Alzheimer's disease.The journal of prevention of Alzheimer's disease · 2025
    Review
  11. Review
  12. Targeting GeneInternational journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jeffrey D RothsteinBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. jrothstein@jhmi.edu.
Victoria BaskervilleBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Sampath RapuriBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Emma MehlhopBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Paymaan Jafar-NejadIonis Pharmaceuticals, Carlsbad, CA, 92010, USA.
Frank RigoIonis Pharmaceuticals, Carlsbad, CA, 92010, USA.
Frank BennettIonis Pharmaceuticals, Carlsbad, CA, 92010, USA.
Sarah MizielinskaUK Dementia Research Institute at King's College London, London, UK.
Adrian IsaacsUK Dementia Research Institute at UCL, London, UK.
Alyssa N CoyneBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. acoyne3@jhmi.edu.ORCID 0000-0002-3658-5325
Johns Hopkins University · USIonis Pharmaceuticals (United States) · USAllen Institute for Brain Science · USKing's College London · GBUK Dementia Research Institute · GB

Funding

Mechanisms of impaired ESCRT-III nuclear surveillance in ALS/FTDR01NS132836 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Alyssa Coyne · 2023 to 2026
$2.3M
Mechanisms of nuclear pore complex homeostasis and injury in ALS/FTD and related neurodegenerative diseasesR00NS123242 · NINDS · JOHNS HOPKINS UNIVERSITY · PI COYNE, ALYSSA · 2022 to 2024
$747k
NINDS NIH HHS R00 NS123242NINDS NIH HHS R01 NS132836
6 · The paper itself

Abstract

The G

Indexed as

Amyotrophic Lateral SclerosisFrontotemporal DementiaInduced Pluripotent Stem CellsC9orf72 ProteinDipeptidesDNA-Binding ProteinsHumansNeuronsOligonucleotides, AntisenseRNA, AntisenseC9orf72 ProteinC9orf72 protein, humanDipeptidesDNA-Binding ProteinsOligonucleotides, AntisenseRNA, AntisenseALSAntisense oligonucleotidesC9orf72Induced pluripotent stem cell derived neuronsRepeat RNATDP-43

Identifiers

PMID38019311
PMCPMC10840905
OpenAlexW4389140131

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.