Evidence map›Paper›PMID 38020198›Full record

ArticleJournal of diabetes research2023

The Effects of Antioxidants and Pulsed Magnetic Fields on Slow and Fast Skeletal Muscle Atrophy Induced by Streptozotocin: A Preclinical Study.

Bora Tastekin, Aykut Pelit, Tugce Sapmaz, Alper Celenk, Muhammed Majeed, Lakshmi Mundkur, Kalyanam Nagabhushanam

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Bora TastekinDepartment of Biophysics, Faculty of Medicine, Cukurova University, Adana, Türkiye.ORCID https://orcid.org/0000-0003-0178-8656
Aykut PelitDepartment of Biophysics, Faculty of Medicine, Cukurova University, Adana, Türkiye.ORCID https://orcid.org/0000-0003-3916-0207
Tugce SapmazDepartment of Histology and Embryology, Faculty of Medicine, Cukurova University, Adana, Türkiye.ORCID https://orcid.org/0000-0001-6927-3582
Alper CelenkDepartment of Histology and Embryology, Faculty of Medicine, Cukurova University, Adana, Türkiye.ORCID https://orcid.org/0000-0002-9669-9535
Muhammed MajeedSami-Sabinsa Group Ltd., 19/1 & 19/2 I Main, II Phase, Peenya Industrial Area, Bangalore, India.ORCID https://orcid.org/0000-0002-1690-7470
Lakshmi MundkurSami-Sabinsa Group Ltd., 19/1 & 19/2 I Main, II Phase, Peenya Industrial Area, Bangalore, India.ORCID https://orcid.org/0000-0003-2928-1726
Kalyanam NagabhushanamSabinsa Corporation, 20 Lake Drive, East Windsor, New Jersey, USA.ORCID https://orcid.org/0000-0001-9470-4110
Cukurova University · TRSabin Vaccine Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Results: Our findings suggest that antioxidants and PMF may alleviate impaired protein synthesis and degradation pathways in skeletal muscle atrophy. PTS showed a positive effect on the anabolic pathway, while RSV and PMF demonstrated potential for ameliorating the catabolic pathway. Notably, the combination therapy of antioxidants and PMF exhibited a stronger ameliorative effect on skeletal muscle atrophy than either intervention alone. Conclusion: The present results highlight the benefits of employing a multimodal approach, involving both antioxidant and PMF therapy, for the management of muscle-wasting conditions. These treatments may have potential therapeutic implications for skeletal muscle atrophy.

Indexed as

AntioxidantsMuscular AtrophyHumansMagnetic FieldsMuscle, SkeletalStreptozocinAntioxidantsStreptozocin

Identifiers

PMID38020198
PMCPMC10661870
OpenAlexW4388629107

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.