Evidence mapPaperPMID 38020665Full record

ReviewFrontiers in neurology2023

Advancements in dendritic cell vaccination: enhancing efficacy and optimizing combinatorial strategies for the treatment of glioblastoma.

Robert C Subtirelu, Eric M Teichner, Arjun Ashok, Chitra Parikh, Sahithi Talasila, Irina-Mihaela Matache, Ahab G Alnemri, Victoria Anderson, Osmaan Shahid, Sricharvi Mannam and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Autologous tumor lysate-loaded dendritic cell vaccination in glioblastoma patients: a systematic review of literature.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Robert C SubtireluDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Eric M TeichnerSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
Arjun AshokSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
Chitra ParikhSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
Sahithi TalasilaSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
Irina-Mihaela MatacheDepartment of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Ahab G AlnemriDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Victoria AndersonSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
Osmaan ShahidDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Sricharvi MannamDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Andrew LeeDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Thomas WernerDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Mona-Elisabeth RevheimDivision of Technology and Innovation, Oslo University Hospital, Oslo, Norway.
Abass AlaviDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
Hospital of the University of Pennsylvania · USThomas Jefferson University · USCarol Davila University of Medicine and Pharmacy · ROOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastomas (GBM) are highly invasive, malignant primary brain tumors. The overall prognosis is poor, and management of GBMs remains a formidable challenge, necessitating novel therapeutic strategies such as dendritic cell vaccinations (DCVs). While many early clinical trials demonstrate an induction of an antitumoral immune response, outcomes are mixed and dependent on numerous factors that vary between trials. Optimization of DCVs is essential; the selection of GBM-specific antigens and the utilization of

Indexed as

antigen loadingdendritic cell vaccinationglioblastomaimmunotherapypositron emission tomography

Identifiers

PMID38020665
PMCPMC10644823
OpenAlexW4388043161

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.