Evidence map›Paper›PMID 38026432›Full record

ArticleFrontiers in public health2023

Adverse reactions following COVID-19 vaccine among healthcare professionals working in Ethiopia: a facility-based cross-sectional study.

Adisu Asefa, Nitsuh Derjachew, Abebe Muche Belete, Feredegn Talargia, Daniel Molla Melese, Bekalu Getachew

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adisu AsefaDepartment of Biomedical Science, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Nitsuh DerjachewDepartment of Public Health, College of Health Science, Gamby Medical and Business College, Bahir Dar, Ethiopia.
Abebe Muche BeleteDepartment of Biomedical Science, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Feredegn TalargiaDepartment of Biomedical Science, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Daniel Molla MeleseDepartment of Biomedical Science, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Bekalu GetachewDepartment of Biomedical Science, College of Medicine, Jimma University, Jimma, Ethiopia.
Debre Berhan University · ETJimma University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background of the study: One of the best medical approaches for halting the spread of infectious diseases is vaccination. During the COVID-19 pandemic, healthcare workers (HCWs) were a high-risk population. Due to their susceptibility in terms of their working environment, front-line healthcare personnel should receive vaccinations before others. Objective: The purpose of this study was to assess the adverse reactions to COVID-19 vaccines among Ethiopian healthcare professionals in 2022. Methods: A facility-based cross-sectional study design was conducted in Addis Ababa Health Facilities, Ethiopia. A total of 290 health professionals who were vaccinated during the study period were involved. Data entry was done by Epidata (version 3.1) and analyzed using SPSS software version 26. Bivariable analysis was conducted and a Results: A total of 277 study participants were successfully involved in the study, yielding a response rate of 95.5%. The study participants comprised 123 (44.4%) women and 154 (55.6%) men. The majority of them (202, 72.9%) had received the Oxford AstraZeneca vaccine. Among the 277 study participants, 142 (51.3%) had developed adverse reactions associated with vaccination. Of these, 81 (29.2%) had moderate adverse reactions. Only 2 (0.7%) had developed adverse reactions that led to hospitalization. The most reported short-term adverse reactions were injection site pain (151, 54.5%), headache (114, 41.2%), fever (104, 37.5%), fatigability and tiredness (94, 33.9%), chills (92, 33.2%), muscle pain (79, 28.5%), and decreased sleep quality (34, 12.3%). The multivariable logistic regression showed that the odds of having an adverse reaction were 1.501 times higher among women than men (AOR = 1.501, 95% CI [1.08, 2.754]). Conclusion and recommendations: This study revealed that adverse effects following the COVID-19 vaccine were moderate in magnitude and minimal in severity. This study showed that adverse reactions that led to hospitalization were rare. Based on the findings of this study, it is recommended that national, multicenter, prospective, and randomized studies be conducted to assess the independent association of each vaccine.

Indexed as

COVID-19COVID-19 VaccinesCross-Sectional StudiesDelivery of Health CareEthiopiaFatigueFemaleHealth PersonnelHumansMalePandemicsProspective StudiesCOVID-19 Vaccinescorona virusCOVID-19 vaccinehealthcare professionalsOxford AstraZenecavaccine

Identifiers

PMID38026432
PMCPMC10654621
OpenAlexW4388298541

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.