Evidence map›Paper›PMID 38029230›Full record

ReviewAdvances in pharmacological and pharmaceutical sciences2023

Use of Monoterpenes as Potential Therapeutics in Diabetes Mellitus: A Prospective Review.

Leonardo da Rocha Sousa, Nildomar Ribeiro Viana, Angélica Gomes Coêlho, Celma de Oliveira Barbosa, Débora Santos Lula Barros, Maria do Carmo de Carvalho E Martins, Ricardo Martins Ramos, Daniel Dias Rufino Arcanjo

Open access · goldAbstract readReview
In one paragraph

Review in Advances in pharmacological and pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. α-Pinene, a Main Component ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Leonardo da Rocha SousaLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0003-2406-0369
Nildomar Ribeiro VianaLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0002-7852-1477
Angélica Gomes CoêlhoLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0002-4024-7652
Celma de Oliveira BarbosaLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0002-8700-9010
Débora Santos Lula BarrosDepartment of Pharmacy, University of Brasilia, Brasília, Brazil.ORCID https://orcid.org/0000-0001-6459-7457
Maria do Carmo de Carvalho E MartinsLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0002-9107-2485
Ricardo Martins RamosLaBME-Laboratory of Molecular Biology and Epidemiology, Federal Institute of Education, Science and Technology of Piauí-Campus Teresina Central, Teresina, Brazil.ORCID https://orcid.org/0000-0003-2016-3344
Daniel Dias Rufino ArcanjoLAFMOL-Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina, Brazil.ORCID https://orcid.org/0000-0001-7021-2744
Universidade Federal do Piauí · BRInstituto Federal do Piauí · BRUniversidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoterpenes are secondary metabolites of plants belonging to the terpenoid class of natural products. They are the most abundant components of essential oils that are generally considered to have various pharmacological properties. These compounds are reported to have antidiabetic effects in recent years. Due to nature's complex biosynthetic machinery, they also exhibit a reasonable degree of structural complexity/diversity for further analysis in structure-activity studies. Therefore, monoterpenes as antidiabetic agents have been investigated by recent in vitro and in vivo studies extensively reported in the scientific literature and claimed by patent documents. The purpose of this survey is to provide a comprehensive and prospective review concerning the potential applications of monoterpenes in the treatment of diabetes. The data for this research were collected through the specialized databases PubMed, Scopus, Web of Science, and ScienceDirect between the years 2014 and 2022, as well as the patent databases EPO, WIPO, and USPTO. The research used 76 articles published in the leading journals in the field. The main effect observed was the antidiabetic activity of monoterpenes. This review showed that monoterpenes can be considered promising agents for prevention and/or treatment of diabetes as well as have a marked pharmaceutical potential for the development of bioproducts for therapeutics applications.

Identifiers

PMID38029230
PMCPMC10665111
OpenAlexW4388693250

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.