Evidence map›Paper›PMID 38033396›Full record

ArticleInternational journal of pharmaceutics: X2023

Polydopamine-activated celastrol carbon dots for synergistic chemotherapy-photothermal therapy of tumors.

Ping Sheng, Chao Bu, Tanyue Hui, Lili Zhou, Hao Chen, Guoliang Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutics: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Multifunctional BiInternational journal of pharmaceutics: X · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ping ShengCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Chao BuCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Tanyue HuiCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Lili ZhouCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Hao ChenCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Guoliang ZhouCollege of life and Health Sciences, Anhui Science and Technology University, Fengyang, 233100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synergistic chemotherapy and photothermal therapy (PTT) holds the promise of addressing the weakness of individualized chemotherapy and PTT. In this study, we synthesized a chemotherapeutic agent, PDA-Ce-CDs, which combines the photothermal conversion ability and the generation of hydroxyl radicals (•OH), enabling synergistic enhancement of antitumor effects. Furthermore, the localized heating effect of NIR radiation promoted the uptake of the PDA-Ce-CDs and enhances the sensitivity of intracellular reactive oxygen species (ROS). Finally, the antitumor activity of the PDA-Ce-CDs was evaluated through cell experiments and tumor-bearing mice experiments, confirming its excellent antitumor efficacy

Indexed as

Carbon dots combined polydopamineCelastrol carbon dotsChemotherapy-photothermal synergistic therapyPolydopamine

Identifiers

PMID38033396
PMCPMC10681950

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.