Evidence map›Paper›PMID 38045306›Full record

ArticlebioRxiv : the preprint server for biology2023

Muscle cofilin alters neuromuscular junction postsynaptic development to strengthen functional neurotransmission.

Briana Christophers, Shannon N Leahy, David B Soffar, Victoria E von Saucken, Kendal Broadie, Mary K Baylies

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Briana ChristophersWeill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, 10065, USA.ORCID 0000-0001-5248-069X
Shannon N LeahyDepartment of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235, USA.ORCID 0000-0002-2987-6191
David B SoffarDevelopmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering, Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-1605-6899
Victoria E von SauckenWeill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, 10065, USA.ORCID 0000-0002-6923-4433
Kendal BroadieDepartment of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235, USA.ORCID 0000-0003-3783-6023
Mary K BayliesBiochemistry, Cell & Developmental Biology, and Molecular Biology (BCMB) program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.ORCID 0000-0002-1626-8138
Memorial Sloan Kettering Cancer Center · USVanderbilt University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
Genetic and Developmental Analyses of Fragile X SyndromeR01MH084989 · NIMH · VANDERBILT UNIVERSITY · PI BROADIE, KENDAL · 2009 to 2021
$5.5M
Mechanisms and Function of Myonuclear PositioningR01AR068128 · NIAMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2014 to 2025
$5.1M
Training Program in Developmental BiologyT32HD060600 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BAO, ZHIRONG, STUHLMANN, HEIDI · 2010 to 2024
$3.5M
Sizing and Scaling in Functional Muscle CellsR35GM141877 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2021 to 2025
$2.2M
The contributions of excitation and contraction to muscle deterioration in a Drosophila model of CFL2 nemaline myopathyF30HD111309 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHRISTOPHERS, BRIANA · 2023 to 2025
$137k
NCI NIH HHS P30 CA008748NIAMS NIH HHS R01 AR068128NICHD NIH HHS F30 HD111309NICHD NIH HHS T32 HD060600NIGMS NIH HHS R35 GM141877NIGMS NIH HHS T32 GM007739NIMH NIH HHS R01 MH084989
6 · The paper itself

Abstract

Cofilin, an actin severing protein, plays critical roles in muscle sarcomere addition and maintenance. Our previous work has shown

Indexed as

actincofilin (CFL)glutamate receptormusclenemaline myopathyneuromuscular junctionpostsynapse

Identifiers

PMID38045306
PMCPMC10690168
OpenAlexW4388906212

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.