Evidence map›Paper›PMID 38047299›Full record

ArticleAmerican journal of physiology. Cell physiology2024

MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport.

Corinne E Farrell, Xiaoning Liu, Nejla Ozbaki Yagan, Amanda C Suda, Debora M Cerqueira, Andrew J Bodnar, Ossama B Kashlan, Arohan R Subramanya, Jacqueline Ho, Michael B Butterworth

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. microRNA and Hypertension.Hypertension (Dallas, Tex. : 1979) · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Corinne E FarrellDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Xiaoning LiuDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Nejla Ozbaki YaganDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Amanda C SudaDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Debora M CerqueiraDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.ORCID 0000-0001-9773-4606
Andrew J BodnarDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Ossama B KashlanRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.ORCID 0000-0003-0537-6720
Arohan R SubramanyaRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-2609-7643
Jacqueline HoDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.ORCID 0000-0001-7115-1381
Michael B ButterworthDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-2173-8333
University of Pittsburgh · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Resource Development CoreU54DK137329 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Gerard L Apodaca · 2023 to 2026
$4.8M
Control of the Renal WNK Signaling Pathway by Phase TransitionsR01DK098145 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AYLIN RACHEL RODAN, AROHAN R SUBRAMANYA · 2014 to 2026
$4.2M
Role of MicroRNAs in Kidney Sodium RegulationR01DK102843 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUTTERWORTH, MICHAEL B · 2015 to 2024
$3.6M
Renal and Epithelial Biology Training ProgramT32DK061296 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2002 to 2022
$3.1M
Regulation of Renal WNK Signaling in Intercalated CellsR01DK119252 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SUBRAMANYA, AROHAN R · 2019 to 2023
$2.0M
ENaC regulation by biliary factorsR01DK125439 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KASHLAN, OSSAMA B · 2020 to 2023
$1.8M
Endothelial miR-17~92 protects against acute kidney injuryR01DK125015 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE, SIMS-LUCAS, SUNDER · 2020 to 2023
$1.5M
Regulation of tubulointerstitial crosstalk by microRNAs in renal fibrosisR01DK137410 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE · 2023 to 2025
$936k
The University of Pittsburgh Summer Research Internship Program kidney workshop (SRIP-Kid)R25DK119180 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACQUELINE HO, Sunder Sims-Lucas · 2021 to 2026
$648k
NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK098145NIDDK NIH HHS R01 DK102843NIDDK NIH HHS R01 DK119252NIDDK NIH HHS R01 DK125015NIDDK NIH HHS R01 DK125439NIDDK NIH HHS R01 DK137410NIDDK NIH HHS R25 DK119180NIDDK NIH HHS T32 DK061296NIDDK NIH HHS U54 DK137329
6 · The paper itself

Abstract

A key regulator of blood pressure homeostasis is the steroid hormone aldosterone, which is released as the final signaling hormone of the renin-angiotensin-aldosterone-signaling (RAAS) system. Aldosterone increases sodium (Na

Indexed as

MicroRNAsAldosteroneAnimalsEpithelial Sodium ChannelsFemaleGlucocorticoidsKidneyMicePhylogenyProtein Serine-Threonine KinasesSodiumAldosteroneEpithelial Sodium ChannelsGlucocorticoidsMicroRNAsProtein Serine-Threonine KinasesSodiumaldosteronemicroRNASGK1sodium

Identifiers

PMID38047299
PMCPMC11192485
OpenAlexW4389307916

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.