SynthesisBMC pediatrics2023
A systematic review with meta-analysis of the relation of aflatoxin B1 to growth impairment in infants/children.
Synthesis in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Workplace exposure to aflatoxins & its health effects: A systematic review.The Indian journal of medical research · 2025Pooled it
- Systematic review and meta-analysis on the prevalence and concentration of aflatoxin BMycotoxin research · 2025Pooled it
- Food-Borne Environmental Contaminants, Intestinal Injury, and Early Childhood Stunting: A Developmental Toxicology Perspective.Birth defects research · 2026Review
- Review
- Occurrence and Co-Occurrence of Regulated and Emerging Mycotoxins in Foods Marketed to U.S. Toddlers.International journal of environmental research and public health · 2026Article
- Genetic mapping and diagnostic marker development for a co-localization interval conferring resistance to both Aspergillus flavus infection and aflatoxin production in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Ambient temperature, rainfall, and adverse maternal and child health outcomes in Nigeria: evidence from a national cross-sectional study.Frontiers in public health · 2026Article
- Genomic and transcriptomic insights into aflatoxin-induced intrahepatic cholangiocarcinoma: an integrated pathway and meta-analysis study.Frontiers in genetics · 2026Article
- The economic crisis in Lebanon and adolescent nutritional health: a multi-mycotoxin exposure and risk assessment of stunting and thinness.Frontiers in nutrition · 2026Article
- Early Childhood Dietary Exposure of Aflatoxins and Fumonisins in Tanzania: Role in Child Stunting and Possible Interventions (2003-2024).Food science & nutrition · 2025Review
- Article
- Preschoolers in severely food insecure Guatemalan Mayan households consume a monotonous grain-based diet.BMC public health · 2025Article
- Monitoring of the Physicochemical Properties and Aflatoxin ofFoods (Basel, Switzerland) · 2025Article
- Article
- Optimization of low-temperature nitrogen plasma in reducing fungi and aflatoxin human exposure through maize.Scientific reports · 2025Article
- Article
- Evaluation of Aflatoxins Occurrence and Exposure in Cereal-Based Baby Foods: An Update Review.Current nutrition reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAflatoxins are regarded as the most potent genotoxic and carcinogenic type of mycotoxins. This meta-analysis was performed to investigate a the relation of aflatoxin B1 (AFB1) to growth measurements of infants/children, including wasting, underweight, stunting, as well as weight-for-age (WAZ), height-for-age (HAZ), and weight-for-height (WHZ) z-scores.
methodsElectronic databases of PubMed, Web of Science, and Scopus were searched to identify related publications. Effect sizes for associations were pooled using the random effects analysis. Subgroup analysis by study design, method used to assess AFB1, and adjustment for covariateswas performed to detect possible sources of heterogeneity.
resultsPooled analysis of available data showed that AFB1 exposure was negatively associated growth z-scores, including WHZ (β = -0.02, 95%CI = -0.07 to 0.03), with WAZ (β = -0.18, 95%CI = -0.33 to -0.02), and HAZ (β = -0.17, 95%CI = -0.30 to -0.03) in infants/children. There was a remarkable heterogeneity among studies on WAZ and HAZ (P ≤ 0.001). In prospective cohort studies, AFB1 exposure was found to be significantly associated with the elevated risk of underweight (OR = 1.20, 95%CI = 1.03 to 1.40) and stunting (OR = 1.21, 95%CI = 1.11 to 1.33).
conclusionsThis meta-analysis highlighted the importance of AFB1 exposure as a potential risk factor for growth impairment in infants/children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.