Evidence map›Paper›PMID 38055798›Full record

ArticleScience translational medicine2023

Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for

Björn Corleis, Constantine N Tzouanas, Marc H Wadsworth, Josalyn L Cho, Alice H Linder, Abigail E Schiff, Björn Zessin, Fabian Stei, Anca Dorhoi, Amy K Dickey and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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  14. Clinicopathological association of CD93 expression in gastric adenocarcinoma.Journal of cancer research and clinical oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Björn CorleisRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-9833-3169
Constantine N TzouanasRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0002-7536-1156
Marc H WadsworthRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-9479-8516
Josalyn L ChoRoy J. and Lucille A. Carver College of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-0367-4495
Alice H LinderRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Abigail E SchiffDepartment of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-7233-489X
Björn ZessinInstitute of Immunology, Friedrich-Loeffler-Institute, Greifswald-Insel Riems, 17493, Germany.
Fabian SteiInstitute of Immunology, Friedrich-Loeffler-Institute, Greifswald-Insel Riems, 17493, Germany.
Anca DorhoiInstitute of Immunology, Friedrich-Loeffler-Institute, Greifswald-Insel Riems, 17493, Germany.
Amy K DickeyRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0003-2979-9664
Benjamin D MedoffDivision of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-2558-0449
Alex K ShalekRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-5670-8778
Douglas S KwonRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-8521-8735
Friedrich-Loeffler-Institut · DEBroad Institute · USHarvard University · USBrigham and Women's Hospital · USMassachusetts General Hospital · USRagon Institute of MGH, MIT and Harvard · USUniversity of Iowa · US

Funding

Impact of smoking and its cessation on systemic and airway immune activationR01DA042685 · NIDA · BOSTON MEDICAL CENTER · PI LIN, NINA H. · 2016 to 2021
$4.0M
HIV and COPD:Immune mediated mechanismsU01HL121827 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KWON, DOUGLAS, MEDOFF, BENJAMIN DAVID · 2013 to 2017
$3.2M
An integrated multiplexed genomic assay for low input clinical samples1U24AI118672 · NIAID · BROAD INSTITUTE, INC. · PI SHALEK, ALEX K · 2015 to 2019
$2.0M
NHLBI NIH HHS U01 HL121827NIAID NIH HHS U24 AI118672NIDA NIH HHS R01 DA042685NIH HHS NIH 1R01DA042685-01NIH HHS NIH 1U01HL121827-01NIH HHS NIH 5U24AI118672NIH HHS NIH DP2OD020839
6 · The paper itself

Abstract

Tobacco smoking doubles the risk of active tuberculosis (TB) and accounts for up to 20% of all active TB cases globally. How smoking promotes lung microenvironments permissive to

Indexed as

Mycobacterium tuberculosisTobacco Smoke PollutionTuberculosisHumansLungMacrophagesMonocytesTobacco Smoke Pollution

Identifiers

PMID38055798
PMCPMC12289333
OpenAlexW4389383576

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.