Evidence map›Paper›PMID 38059359›Full record

ReviewHypertension (Dallas, Tex. : 1979)2024

Endothelin System in Hypertension and Chronic Kidney Disease.

Ernesto L Schiffrin, David M Pollock

Open access · greenAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Salt and chronic kidney disease.Nature reviews. Nephrology · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Endothelin antagonists for hypertension: has their time finally arrived?Clinical science (London, England : 1979) · 2025
    Review
  17. Review
  18. Endothelial dysfunction in chronic kidney disease: a clinical perspective.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ernesto L SchiffrinDepartment of Medicine and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC, Canada (E.L.S.).ORCID 0000-0002-4502-2823
David M PollockDepartment of Medicine, Division of Nephrology, Section of Cardio-Renal Physiology and Medicine, University of Alabama at Birmingham (D.M.P.).ORCID 0000-0002-0233-2362
Jewish General Hospital · CAUniversity of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Prospective Effects of Early Life Stress and Protective Factors on Vascular Function and Inflammation in Young AdulthoodP01HL158500 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jennifer S Pollock · 2023 to 2026
$11.1M
Timing of Diet and Kidney Pathophysiology in Diet-Induced ObesityR01DK134562 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID M POLLOCK, Jennifer S Pollock · 2023 to 2026
$2.6M
NHLBI NIH HHS P01 HL158500NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK134562
6 · The paper itself

Abstract

ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues, which exerts many physiological functions across the body and participates as a mediator in many pathological conditions. ETs exert their effects through ET

Indexed as

HypertensionHypertension, PulmonaryRenal Insufficiency, ChronicEndothelin-1Endothelin Receptor AntagonistsEndothelinsHumansReceptor, Endothelin AReceptors, EndothelinEndothelin-1Endothelin Receptor AntagonistsEndothelinsReceptor, Endothelin AReceptors, Endothelindiabetic nephropathiesendothelin receptor antagonistsglomerulosclerosis, focal segmentalvascular remodeling

Identifiers

PMID38059359
PMCPMC10954415
OpenAlexW4389442055

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.