Evidence map›Paper›PMID 38064039›Full record

ArticleBiological trace element research2024

Low-Dose Hexavalent Chromium Exposure Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Rat Liver.

Xiaoying Li, Ningning Li, Xiuzhi Zhang, Lixia Zhang, Guang Jia, Shanfa Yu

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Mechanisms of Metal-Induced Hepatic Inflammation.Current environmental health reports · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Xiaoying Li *Department of Pathology, Henan Medical College, Zhengzhou, Henan, China.
Ningning Li *Department of Pathology, Henan Medical College, Zhengzhou, Henan, China.
Xiuzhi ZhangDepartment of Pathology, Henan Medical College, Zhengzhou, Henan, China.
Lixia ZhangDepartment of Occupational Health and Environmental Health, College of Public Health, Zhengzhou University, Zhengzhou, China.
Guang JiaDepartment of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing, China.
Shanfa YuSchool of Public Health, Henan Medical College, Zhengzhou, Henan, China. shanfa_yu@126.com.
Nanyang Medical College · CNHenan University of Engineering · CNPeking University · CNZhengzhou University · CN

Funding

National Natural Science Foundation of China U2004202
6 · The paper itself

Abstract

This study investigated the toxic effects of low-dose hexavalent chromium (Cr(VI)) on rat liver. Male specific pathogen-free (SPF) Sprague-Dawley (SD) rats (4-5 weeks of age) were randomly divided into groups: saline, 0.05 mg/kg Cr(VI), and 0.25 mg/kg Cr(VI). The rats were subjected to intratracheal instillation of K

Indexed as

ApoptosisChromiumEndoplasmic Reticulum StressLiverRats, Sprague-DawleyAnimalsDose-Response Relationship, DrugMaleRatsChromiumchromium hexavalent ionApoptosisEndoplasmic reticulum stress (ERS)Hexavalent chromeLiver

Identifiers

PMID38064039
OpenAlexW4389485063

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.