Evidence map›Paper›PMID 38067252›Full record

ArticleCancers2023

Supportive Care in Pediatric Oncology: Opportunities and Future Directions.

Jason L Freedman, Dori M Beeler, Alison Bowers, Natalie Bradford, Yin Ting Cheung, Maya Davies, L Lee Dupuis, Caitlin W Elgarten, Torri M Jones, Tracey Jubelirer and 5 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jason L FreedmanDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-0752-2701
Dori M BeelerDepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC 28204, USA.
Alison BowersCancer and Palliative Care Outcomes Centre, Centre for Children's Health Research, Queensland University of Technology, Brisbane City, QLD 4000, Australia.ORCID 0000-0002-9870-0931
Natalie BradfordCancer and Palliative Care Outcomes Centre, Centre for Children's Health Research, Queensland University of Technology, Brisbane City, QLD 4000, Australia.ORCID 0000-0003-1602-4544
Yin Ting CheungSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-9874-8938
Maya DaviesSchool of Biomedicine, The Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5005, Australia.
L Lee DupuisLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 1A1, Canada.ORCID 0000-0002-7699-1061
Caitlin W ElgartenDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Torri M JonesDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Tracey JubelirerDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Tamara P MillerAflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA 30322, USA.
Priya PatelDepartment of Pharmacy, The Hospital for Sick Children, Toronto, ON M5G 1E8, Canada.ORCID 0000-0002-2872-5412
Charles A PhillipsDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-0391-1673
Hannah R WardillSchool of Biomedicine, The Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-6613-3661
Andrea D OrseyCenter for Cancer and Blood Disorders, Connecticut Children's Medical Center, Hartford, CT 06106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimization of outcomes for pediatric cancer patients relies on the successful advancement of supportive care to ease the treatment burden and mitigate the long-term impacts of cancer therapy. Advancing pediatric supportive care requires research prioritization as well as the development and implementation of innovations. Like the prevailing theme throughout pediatric oncology, there is a clear need for personalized or precision approaches that are consistent, evidence-based, and guided by clinical practice guidelines. By incorporating technology and datasets, we can address questions which may not be feasible to explore in clinical trials. Now is the time to listen to patients' voices by using patient-reported outcomes (PROs) to ensure that their contributions and experiences inform clinical care plans. Furthermore, while the extrapolation of knowledge and approaches from adult populations may suffice in the absence of pediatric-specific evidence, there is a critical need to specifically understand and implement elements of general and developmental pediatrics like growth, nutrition, development, and physical activity into care. Increased research funding for pediatric supportive care is critical to address resource availability, equity, and disparities across the globe. Our patients deserve to enjoy healthy, productive lives with optimized and enriched supportive care that spans the spectrum from diagnosis to survivorship.

Indexed as

clinical practice guidelinesCPGequitynutritionpalliative carepediatric oncologypediatricsPROstem cell transplantsupportive caresurvivorship

Identifiers

PMID38067252
PMCPMC10705083

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.