ArticleJournal of clinical medicine2023
Can the Modified Frailty Index (mFI) Predict Intraoperative and Postoperative Complications in Older Women with Endometrial Cancer Undergoing Laparoscopic or Robotic Surgery? A Multicenter Observational Study.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 8 citations in OpenAlex.
- Development and validation of a nomogram prediction model for postoperative complications in elderly patients with endometrial cancer.Pakistan journal of medical sciences · 2026Article
- The role of pre-operative sit-to-stand assessment in robotic hysterectomy surgical outcomes: An observational cohort study.Gynecologic oncology reports · 2026Article
- Impact of preoperative frailty assessment on peri-operative complications and cancer related outcomes in advanced stage endometrial cancer.Gynecologic oncology reports · 2026Article
- Analgesic efficacy and safety of transversus abdominis plane block versus thoracic paravertebral block in laparoscopic total hysterectomy: propensity score matching and mFI-5 subgroup analysis.American journal of translational research · 2026Article
- Frailty and an Inflammation-Nutrition Composite for Predicting Postoperative Outcomes in Older Patients Undergoing Endometrial Cancer Surgery.Clinical interventions in aging · 2026Article
- [Preoperative frailty and postoperative health outcomes in postmenopausal patients undergoing gynecological cancer surgery: a retrospective observational study].Journal of Korean biological nursing science · 2025Article
- Usefulness of Geriatric Parameters in Preoperative Evaluation of Patients Undergoing Minimally Invasive Surgery for Endometrial Cancer: A Retrospective Cohort Study.Annals of surgical oncology · 2025Article
- Article
- Association of Frailty with Intraoperative Complications in Older Patients Undergoing Elective Non-Cardiac Surgery.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
25 authors at 9 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aims to evaluate the strength of the association between frailty and intraoperative/postoperative complications in patients undergoing minimally invasive surgery (MIS) for endometrial cancer.
methodsIn this retrospective observational multicenter cohort study, frailty was defined beforehand by a modified frailty index (mFI) score of ≥3. Multiple logistic regressions were performed to investigate possible preoperative predictors-including frailty, age, and body mass index-of intraoperative and early (within 30 days from surgery) or delayed (beyond 30 days from surgery) postoperative complications.
resultsThe study involved 577 women, of whom 6.9% (n = 40) were frail with an mFI ≥ 3, while 93.1% (n = 537) were non-frail with an mFI of 0-2. Frail women had a significantly higher rate of intraoperative complications (7.5% vs. 1.7%,
conclusionsFrailty was associated with a significantly higher risk of intraoperative complications in older women undergoing MIS for endometrial cancer. Likewise, increasing age was an independent predictor of early postoperative complications. Our findings support the practice of assessing frailty before surgery to optimize perioperative management in this patient population.
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