ArticlebioRxiv : the preprint server for biology2023
Leptomeningeal Neural Organoid (LMNO) Fusions as Models to Study Meninges-Brain Signaling.
Hannah E Jones, Gabriella L Robertson, Alejandra Romero-Morales, Rebecca O'Rourke, Julie A Siegenthaler, Vivian Gama
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors at 2 institutions in 1 country.
Hannah E JonesUniversity of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Developmental Biology, Aurora, CO 80045 USA.
Gabriella L RobertsonVanderbilt University School of Medicine, Department of Cell and Developmental Biology, Nashville, TN 37232 USA.ORCID 0000-0002-8729-8334 Alejandra Romero-MoralesVanderbilt University School of Medicine, Department of Cell and Developmental Biology, Nashville, TN 37232 USA.
Rebecca O'RourkeUniversity of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Developmental Biology, Aurora, CO 80045 USA.
Julie A SiegenthalerUniversity of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Developmental Biology, Aurora, CO 80045 USA.
Vivian GamaVanderbilt University School of Medicine, Department of Cell and Developmental Biology, Nashville, TN 37232 USA.ORCID 0000-0002-1201-1394 University of Colorado Anschutz Medical Campus · USVanderbilt University · US
Funding
The BCL-2 family controls stem cell identity by regulating mitochondrial dynamics and primingR35GM128915 · NIGMS · VANDERBILT UNIVERSITY · PI Vivian Gama · 2018 to 2026
$3.8MModeling developmental gradients and supportive tissue signaling networks using iPSC-derived forebrain organoids embedded in fluidic hydrogelsRF1MH123971 · NIMH · VANDERBILT UNIVERSITY · PI BELLAN, LEON MARCEL, GAMA, VIVIAN · 2020 to 2020
$2.3MAcquisition of a super-resolution optical microscopeS10OD012324 · OD · VANDERBILT UNIVERSITY · PI TYSKA, MATTHEW J · 2012 to 2012
$1.1MLSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560kCellular mechanisms of perivascular fibroblast development and dependence on PDGF signalingF31NS125875 · NINDS · UNIVERSITY OF COLORADO DENVER · PI JONES, HANNAH ELIZABETH · 2022 to 2024
$100kThe impact of mitochondrial and peroxisomal fission dynamics on metabolic signaling during corticogenesis.F99NS125829 · NINDS · VANDERBILT UNIVERSITY · PI ROBERTSON, GABRIELLA LOU PUIG · 2021 to 2022
$65kNIGMS NIH HHS R35 GM128915NIH HHS S10 OD012324NIH HHS S10 OD021630NIMH NIH HHS RF1 MH123971NINDS NIH HHS F31 NS125875NINDS NIH HHS F99 NS125829
6 · The paper itselfAbstract
Neural organoids derived from human induced pluripotent stem cells (iPSCs) provide a model to study the earliest stages of human brain development, including neurogenesis, neural differentiation, and synaptogenesis. However, neural organoids lack supportive tissues and some non-neural cell types that are key regulators of brain development. Neural organoids have instead been co-cultured with non-neural structures and cell types to promote their maturation and model interactions with neuronal cells. One structure that does not form
Identifiers
PMID38077064
PMCPMC10705555
OpenAlexW4389271646
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390