Evidence map›Paper›PMID 38077523›Full record

ArticleAnalytical cellular pathology (Amsterdam)2023

Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA-JPX/miR-146b Axis.

Tongda Xu, Yuanyuan Zhang, Gege Liao, Haochen Xuan, Jie Yin, Jieli Bao, Yang Liu, Dongye Li

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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  5. WTAP-mediated mJournal of translational medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tongda XuInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.ORCID https://orcid.org/0000-0002-5594-3992
Yuanyuan ZhangInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.
Gege LiaoInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.ORCID https://orcid.org/0000-0002-2624-2417
Haochen XuanDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.ORCID https://orcid.org/0000-0002-2017-9285
Jie YinDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Jieli BaoDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yang LiuInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.ORCID https://orcid.org/0000-0003-1191-3705
Dongye LiInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.ORCID https://orcid.org/0000-0003-4875-0209
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In the present study, we aimed to find out whether luteolin (Lut) pretreatment could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just proximal to XIST (JPX)/microRNA-146b (miR-146b) axis. Methods: We established the models Results: miR-146b was demonstrated to bind and recognize the JPX sequence site by dual luciferase reporter gene assay. The expression level of miR-146b was corroborated to be enhanced by H/R using RT-qPCR ( Conclusion: Our results demonstrated that

Indexed as

MicroRNAsMyocardial Reperfusion InjuryRNA, Long NoncodingAnimalsAnnexin A5Apoptosisbcl-2-Associated X ProteinCaspase 3Caspase 9LuciferasesLuteolinMiceMice, Inbred C57BLMyocytes, CardiacProto-Oncogene Proteins c-bcl-2Annexin A5bcl-2-Associated X ProteinCaspase 3Caspase 9LuciferasesLuteolinMicroRNAsProto-Oncogene Proteins c-bcl-2RNA, Long Noncoding

Identifiers

PMID38077523
PMCPMC10710365
OpenAlexW4389263861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.