Evidence map›Paper›PMID 38079574›Full record

ArticleACS synthetic biology2024

A Standardized Set of MoClo-Compatible Inducible Promoter Systems for Tunable Gene Expression in Yeast.

Richard O'Laughlin, Quoc Tran, Andrew Lezia, Wasu Ngamkanjanarat, Philip Emmanuele, Nan Hao, Jeff Hasty

Open access · greenAbstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Sensing and Reprogramming Surface Receptor Activation With Synthetic Transcriptional Circuits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Richard O'LaughlinDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.ORCID 0000-0002-7552-5421
Quoc TranDepartment of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, United States.ORCID 0009-0004-3928-5493
Andrew LeziaDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.ORCID 0000-0001-8068-8834
Wasu NgamkanjanaratDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.
Philip EmmanueleDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.
Nan HaoDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.
Jeff HastyDepartment of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.
University of California San Diego · US

Funding

Network-Driven Dynamics of Replicative AgingR01AG056440 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEFF M HASTY, Nan Hao · 2017 to 2026
$5.6M
Dynamically compartmentalized control of gene expression by messenger ribonucleoprotein granulesR01GM111458 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAO, NAN · 2014 to 2022
$3.4M
Reprogramming cell-fate decisions through predictive modeling and synthetic biologyR01GM144595 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAO, NAN, HASTY, JEFF M · 2022 to 2025
$2.8M
NIA NIH HHS R01 AG056440NIGMS NIH HHS R01 GM111458NIGMS NIH HHS R01 GM144595
6 · The paper itself

Abstract

Small-molecule control of gene expression underlies the function of numerous engineered gene circuits that are capable of environmental sensing, computation, and memory. While many recently developed inducible promoters have been tailor-made for bacteria or mammalian cells, relatively few new systems have been built for

Indexed as

Metabolic EngineeringSaccharomyces cerevisiaeGene Expressionauxinchemically induced proximity (CIP)inducible promotermodular cloning (MoClo)toolkityeast

Identifiers

PMID38079574
PMCPMC11283237
OpenAlexW4389537407

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.