Evidence map›Paper›PMID 38084142›Full record

ArticlePeerJ2023

PER2 regulates odontoblastic differentiation of dental papilla cells

Haozhen Ma, Xinyue Sheng, Wanting Chen, Hongwen He, Jiawei Liu, Yifan He, Fang Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Haozhen MaHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Xinyue ShengHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Wanting ChenHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Hongwen HeHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Jiawei LiuHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Yifan HeHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Fang HuangHospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNHospital of Stomatology, Sun Yat-sen University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dental papilla cells (DPCs) are one of the key stem cells for tooth development, eventually forming dentin and pulp. Previous studies have reported that PER2 is expressed in a 24-hour oscillatory pattern in DPCs Methods: We monitored the expression of PER2 in DPCs differentiated Results: PER2 expression was considerably elevated throughout the odontoblastic differentiation of DPCs Conclusion: Overall, we demonstrated that PER2 positively regulates the odontogenic differentiation of DPCs, and the mechanism may be related to mitochondrial function as shown by intracellular ATP content and ROS levels.

Indexed as

Dental PapillaOdontoblastsAdenosine TriphosphateCell DifferentiationReactive Oxygen SpeciesAdenosine TriphosphateReactive Oxygen SpeciesATPDental papilla cellsIn vitroOdontoblastic differentiationPER2ROSTooth development

Identifiers

PMID38084142
PMCPMC10710777
OpenAlexW4389443999

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.