ArticlePlant physiology2024
m6A RNA methylation counteracts dark-induced leaf senescence in Arabidopsis.
Article in Plant physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- RNA m6A methylation fine-tunes the jasmonic acid biosynthesis pathway to modulate plant aging.The Plant cell · 2026Article
- Advances in the study of the role of epigenetic mechanisms in plant growth and response to stress.Horticulture research · 2026Article
- Genome-wide association study and KASP development for growth and leaf traits in Populus deltoides.BMC genomics · 2026Article
- From signals to solutions: stress-induced leaf senescence and synthetic biology and AI approaches for crop resilience.Molecular horticulture · 2026Review
- Dual Roles of mCells · 2026Review
- Regulatory Role of Jasmonate Signaling in Dark-, Drought-, and Salt-Induced Leaf Senescence.International journal of molecular sciences · 2026Review
- The role of NTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Molecular mechanisms and crop improvement potential of RNA NaBIOTECH · 2025Review
- Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights.Journal of advanced research · 2025Review
- Emerging Orchestrator of Ecological Adaptation: mMolecular ecology · 2025Review
- Differential Sensitivity of Photosynthetic Electron Transport to Dark-Induced Senescence in Wheat Flag Leaves.BMC plant biology · 2025Article
- Genome-Wide Identification and Expression Analysis of mInternational journal of molecular sciences · 2025Article
- RNA mNature plants · 2025Review
- The roles of a MiRNA and its targeted methyltransferase 3 in carotenoid accumulation in adductor muscles of QN orange scallops.BMC genomics · 2025Article
- Writers, readers, and erasers of N6-Methyladenosine (m6A) methylomes in oilseed rape: identification, molecular evolution, and expression profiling.BMC plant biology · 2025Article
- Crosstalk between RNA mPlant communications · 2024Review
- Knockdown ofPlants (Basel, Switzerland) · 2024Article
- Identification of mBiochemistry and biophysics reports · 2024Article
- Detection, distribution, and functions of RNAFrontiers in plant science · 2024Review
- Genome-wide identification and functional analysis of mRNA mFrontiers in plant science · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Senescence is an important physiological process which directly affects many agronomic traits in plants. Senescence induces chlorophyll degradation, phytohormone changes, cellular structure damage, and altered gene regulation. Although these physiological outputs are well defined, the molecular mechanisms employed are not known. Using dark-induced leaf senescence (DILS) as the experimental system, we investigated the role of N6-methyladenosine (m6A) mRNA methylation during senescence in Arabidopsis (Arabidopsis thaliana). Plants compromised in m6A machinery components like METHYLTRANSFERASE A (mta mutant) and VIRILIZER1 (vir-1 mutant) showed an enhanced DILS phenotype. This was accompanied by compromised chloroplast and photosynthesis performance in mta as well as accumulation of senescence-promoting camalexin and phytohormone jasmonic acid after dark treatment. m6A levels increased during DILS and destabilized senescence-related transcripts thereby preventing premature aging. Due to inefficient decay, senescence-related transcripts like ORESARA1 (ORE1), SENESCENCE-ASSOCIATED GENE 21 (SAG21), NAC-like, activated by AP3/PI (NAP), and NONYELLOWING 1 (NYE1) over-accumulated in mta thereby causing accelerated senescence during DILS. Overall, our data propose that m6A modification is involved in regulating the biological response to senescence in plants, providing targets for engineering stress tolerance of crops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.