Evidence map›Paper›PMID 38085705›Full record

ArticleDiabetes care2024

Assessment of Glycemic Control by Continuous Glucose Monitoring, Hemoglobin A1c, Fructosamine, and Glycated Albumin in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes.

Candice Y Kaminski, Rodolfo J Galindo, Jose E Navarrete, Zohyra Zabala, Bobak Moazzami, Amany Gerges, Rozalina G McCoy, Maya Fayfman, Priyathama Vellanki, Thaer Idrees and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05741489 (Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05741489 nacompletednot on this map

Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes

TypeinterventionalSponsorEmory UniversityRan2022 to 2023Enrolled40ConditionsEnd Stage Kidney DiseaseArmsContinuous glucose monitoring (CGM)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Observational
  10. Review
  11. Article
  12. Article
  13. Time to Plan for Continuous Glucose Monitoring in Dialysis-Dependent Kidney Failure.Journal of the American Society of Nephrology : JASN · 2025
    Article
  14. Observational
  15. Article
  16. Review
  17. Diabetes and Glucose Management in People on Hemodialysis.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Candice Y KaminskiEmory University School of Medicine, Atlanta, GA.
Rodolfo J GalindoDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0002-9295-3225
Jose E NavarreteDivision of Nephrology, Department of Medicine, Emory University, Atlanta, GA.
Zohyra ZabalaDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0003-4208-6087
Bobak MoazzamiDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.
Amany GergesDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.
Rozalina G McCoyDivision of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-2289-3183
Maya FayfmanDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0002-8733-3160
Priyathama VellankiDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0002-6544-015X
Thaer IdreesDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0001-9036-995X
Limin PengEmory University Rollins School of Public Health, Atlanta, GA.
Guillermo E UmpierrezDivision of Endocrinology, Department of Medicine, Emory University, Atlanta, GA.ORCID 0000-0002-3252-5026
Emory University · USUniversity of Maryland, Baltimore · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Comparative Effectiveness and Safety of Osteoporosis Drug TherapiesR01AG079113 · NIA · MAYO CLINIC ROCHESTER · PI Juan P Brito Campana, Rozalina Grubina McCoy · 2022 to 2026
$3.3M
Developing statistical analysis and prediction tools for continuous glucose monitoring (CGM) use in hospitalized patients with diabetesR01DK136023 · NIDDK · EMORY UNIVERSITY · PI Limin Peng · 2024 to 2026
$1.1M
Use of Continuous Glucose Monitoring (CGM) in End-Stage Renal Disease(ESRD) Patients with Type 2 DiabetesK23DK123384 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2020 to 2024
$934k
Predicting the Risk of Severe Hypoglycemic and Hyperglycemic Events in Adults with DiabetesK23DK114497 · NIDDK · MAYO CLINIC ROCHESTER · PI MCCOY, ROZALINA GRUBINA · 2017 to 2021
$846k
Epigenetic Markers of Short- and Long- Term Near-Normoglycemia Remission in Patients with Ketosis-Prone DiabetesK23DK113241 · NIDDK · EMORY UNIVERSITY · PI VELLANKI, PRIYATHAMA · 2019 to 2021
$646k
Community Paramedicine Program to Improve Diabetes Management among Adults Experiencing Severe HypoglycemiaR03DK127010 · NIDDK · MAYO CLINIC ROCHESTER · PI MCCOY, ROZALINA GRUBINA · 2021 to 2022
$239k
NCATS NIH HHS UL1 TR002377NCATS NIH HHS UL1 TR002378NIA NIH HHS R01 AG079113NIDDK NIH HHS K23 DK113241NIDDK NIH HHS K23 DK114497NIDDK NIH HHS K23 DK123384NIDDK NIH HHS P30 DK111024NIDDK NIH HHS R01 DK136023NIDDK NIH HHS R03 DK127010
6 · The paper itself

Abstract

objectivePatients with diabetes and end-stage kidney disease (ESKD) may experience "burnt-out diabetes," defined as having an HbA1c value <6.5% without antidiabetic therapy for >6 months. We aim to assess glycemic control by continuous glucose monitoring (Dexcom G6 CGM) metrics and glycemic markers in ESKD patients on hemodialysis with burnt-out diabetes. RESEARCH DESIGN AND

methodsIn this pilot prospective study, glycemic control was assessed by continuous glucose monitoring (CGM), HbA1c measures, and glycated albumin and fructosamine measurements in patients with burnt-out diabetes (n = 20) and without a history of diabetes (n = 20).

resultsPatients with burnt-out diabetes had higher CGM-measured daily glucose levels, lower percent time in the range 70-180 mg/dL, higher percent time above range (>250 mg/dL), and longer duration of hyperglycemia >180 mg/dL (hours/day) compared with patients without diabetes (all P < 0.01). HbA1c and fructosamine levels were similar; however, patients with burnt-out diabetes had higher levels of glycated albumin than did patients without diabetes.

conclusionsThe use of CGM demonstrated that patients with burnt-out diabetes have significant undiagnosed hyperglycemia. CGM and glycated albumin provide better assessment of glycemic control than do values of HbA1c and fructosamine in patients with ESKD.

Indexed as

Diabetes MellitusHyperglycemiaKidney Failure, ChronicBlood GlucoseBlood Glucose Self-MonitoringContinuous Glucose MonitoringFructosamineGlycated HemoglobinGlycated Serum AlbuminGlycation End Products, AdvancedGlycemic ControlHumansProspective StudiesSerum AlbuminBlood GlucoseFructosamineGlycated HemoglobinGlycated Serum AlbuminGlycation End Products, AdvancedSerum Albumin

Identifiers

PMID38085705
PMCPMC11148628
OpenAlexW4389612124

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.