Evidence map›Paper›PMID 38092564›Full record

ArticleJournal of virology2023

Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an

Priyanka Shukla Bajpai, Laura Collignon, Christina Sølund, Lone Wulff Madsen, Peer Brehm Christensen, Anne Øvrehus, Nina Weis, Kenn Holmbeck, Ulrik Fahnøe, Jens Bukh

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Priyanka Shukla BajpaiCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-2607-0141
Laura CollignonCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Christina SølundCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Lone Wulff MadsenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Peer Brehm ChristensenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Anne ØvrehusDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Kenn HolmbeckCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Ulrik FahnøeCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Jens BukhCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-7815-4806
University of Copenhagen · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceHCV genotype 3b is a difficult-to-treat subtype, associated with accelerated progression of liver disease and resistance to antivirals. Moreover, its prevalence has significantly increased among persons who inject drugs posing a serious risk of transmission in the general population. Thus, more genetic information and antiviral testing systems are required to develop novel therapeutic options for this genotype 3 subtype. We determined the complete genomic sequence and complexity of three genotype 3b isolates, which will be beneficial to study its biology and evolution. Furthermore, we developed a full-length

Indexed as

Genome, ViralHepacivirusHepatitis CAnimalsAntiviral AgentsDNA, ComplementaryGenotypeHumansMiceSequence AnalysisAntiviral AgentsDNA, Complementarygenotype 3bHCVhepatitis C virushuman-liver chimeric micein vivo infectious cDNA cloneRASresistance-associated substitutions

Identifiers

PMID38092564
PMCPMC10734419
OpenAlexW4388865516

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.