Evidence map›Paper›PMID 38096105›Full record

Trial reportAnnals of the American Thoracic Society2024

Adjunctive Systemic Corticosteroids for Pulmonary Exacerbations of Cystic Fibrosis.

Oliver J McElvaney, Sonya L Heltshe, Katherine Odem-Davis, Natalie E West, Don B Sanders, Barbra Fogarty, Donald R VanDevanter, Patrick A Flume, Christopher H Goss

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of the American Thoracic Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Correlates of FEV₁ deficit in pulmonary exacerbations of cystic fibrosis and associated clinical outcomes.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2026
    Trial
  3. Pulmonary exacerbations in primary ciliary dyskinesia.European journal of pediatrics · 2026
    Review
  4. Evaluating the association of antibiotic spectrum and treatment responses of cystic fibrosis pulmonary exacerbations.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2026
    Article
  5. Article
  6. Oroxylin A FromCanadian respiratory journal · 2026
    Article
  7. Cystic Fibrosis Year in Review 2024.Pediatric pulmonology · 2025
    Review
  8. Article
  9. Cystic fibrosis year in review 2023.Pediatric pulmonology · 2024
    Review
  10. STOP Using Corticosteroids in Cystic Fibrosis Pulmonary Exacerbations.Annals of the American Thoracic Society · 2024
    Article
  11. Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Oliver J McElvaneyCystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington.
Sonya L HeltsheCystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington.
Katherine Odem-DavisCystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington.
Natalie E WestDepartment of Medicine, Johns Hopkins University, Baltimore, Maryland.
Don B SandersDepartment of Pediatrics, Indiana University, Indianapolis, Indiana.
Barbra FogartyCystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington.
Donald R VanDevanterDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio; and.
Patrick A FlumeDepartment of Pediatrics and.
Christopher H GossCystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington.
Cystic Fibrosis Foundation · USCase Western Reserve University · USIndiana University – Purdue University Indianapolis · USJohns Hopkins University · USMedical University of South Carolina · USUniversity of Washington · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
NCATS NIH HHS UL1 TR001450NIDDK NIH HHS P30 DK089507NIH HHS P30 DK089507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenal Cortex HormonesCystic FibrosisDisease ProgressionAdolescentAdultAnti-Bacterial AgentsDrug Therapy, CombinationFemaleForced Expiratory VolumeHumansMalePropensity ScoreTreatment OutcomeYoung AdultAdrenal Cortex HormonesAnti-Bacterial AgentsCFclinical trialcorticosteroidsPExrespiratory infection

Identifiers

PMID38096105
PMCPMC11109904
OpenAlexW4389727318

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.