Evidence map›Paper›PMID 38098220›Full record

ArticleAging cell2024

MiR-203 improves cardiac dysfunction by targeting PARP1-NAD

Limin Zhao, Pingping Tang, Yuan Lin, Menghan Du, Huimin Li, Lintong Jiang, Henghui Xu, Heyang Sun, Jingjing Han, Zeqi Sun and 6 more

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Multicellular senescence programs in the aged heart.Journal of molecular and cellular cardiology plus · 2026
    Review
  3. Article
  4. Article
  5. Cellular and molecular mechanisms underlying cardiovascular aging.Cellular & molecular biology letters · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Molecular Morbidity Score-Can MicroRNAs Assess the Burden of Disease?International journal of molecular sciences · 2024
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Limin ZhaoDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Pingping TangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Yuan LinDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Menghan DuDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Huimin LiDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Lintong JiangDepartment of Pharmacy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Henghui XuDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Heyang SunDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Jingjing HanDepartment of Pharmacy, Caoxian People's Hospital, Heze, China.
Zeqi SunDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Run XuDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Han LouDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Zhouxiu ChenDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Philipp KopylovDepartment of Preventive and Emergency Cardiology, Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Xin LiuDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Yong ZhangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine- Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.ORCID 0000-0002-8754-8938
Harbin Medical University · CNCixian People's Hospital · CNSechenov University · RU

Funding

HMU Marshal Initiative Funding HMUMIF-21022National Natural Science Foundation of China 82270396National Natural Science Foundation of China 82273919Science Foundation for the Excellent Youth Scholars of Heilongjiang Province JJ2023YX0509
6 · The paper itself

Abstract

Heart aging is a prevalent cause of cardiovascular diseases among the elderly. NAD

Indexed as

Heart DiseasesMicroRNAsAgedAgingAnimalsCellular SenescenceHumansMiceMice, TransgenicMyocytes, CardiacNADPoly (ADP-Ribose) Polymerase-1MicroRNAsMIRN203 microRNA, humanMIRN203 microRNA, mouseNADPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1heart agingmiR-203mitochondrial functionNAD+PARP1

Identifiers

PMID38098220
PMCPMC10928583
OpenAlexW4389792159

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.