ArticleFrontiers in neurology2023
Chronic kidney disease as a predictive factor for poor prognosis in traumatic brain injury among older adults: a case-control study.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 4 citations in OpenAlex.
- Impact of Premorbid Function and Comorbidities in Geriatric Traumatic Brain Injury Patients: A Systematic Review.Cureus · 2026Review
- Effect of Creatinine on Various Clinical Outcomes in Patients with Severe Traumatic Brain Injury (TBI).Metabolites · 2025Article
- Article
- Associations between Glasgow Coma Scale trajectories and 28-day survival rate in patients with sepsis-associated encephalopathy: insights from longitudinal group trajectory modeling.Frontiers in neurology · 2025Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Traumatic brain injury (TBI) is a highly prevalent neurological disorder that affects a gradually increasing proportion of older adults. Chronic kidney disease (CKD) significantly contributes to global years of life lost, with an estimated one-tenth of the global population affected by CKD. However, it remains unclear whether CKD impacts TBI prognosis. We conducted a case-control study to investigate the clinical outcomes of TBI patients with or without CKD comorbidity and identified the risk factors associated with a poor prognosis. Methods: From January 2017 through April 2023, 11 patients with TBI and CKD were included, and 27 control TBI cases with normal kidney function were matched by age, gender, and admission Glasgow Coma Scale (GCS) score as the control group. Results: The CKD TBI group had a significantly lower GCS score upon discharge (7.1 ± 5.9) compared to the non-CKD TBI group (13.1 ± 2.6) ( Conclusion: TBI patients comorbid with CKD have a poorer prognosis than those with normal kidney function.
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