ArticlebioRxiv : the preprint server for biology2023
Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain.
Sarah C Hopp, Juliet Garcia Rogers, Sabrina Smith, Gabriela Campos, Henry Miller, Savannah Barannikov, Eduardo Gutierrez Kuri, Hu Wang, Xianlin Han, Kevin F Bieniek and 2 more
Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 2 institutions in 2 countries.
Sarah C HoppGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.ORCID 0000-0001-5228-0022
Juliet Garcia RogersGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.
Sabrina SmithGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.
Gabriela CamposSam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.
Henry MillerSam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.ORCID 0000-0003-3756-3918
Savannah BarannikovDepartment of Pathology and Laboratory Science, University of Texas Health Science Center San Antonio.
Eduardo Gutierrez KuriDepartment of Pharmacology, University of Texas Health Science Center San Antonio.
Hu WangSam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.
Xianlin HanGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.
Kevin F BieniekGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.ORCID 0000-0003-4922-864X
Susan T WeintraubDepartment of Biochemistry & Structural Biology, University of Texas Health Science Center San Antonio.ORCID 0000-0002-8328-7814
Juan Pablo PalaviciniSam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.ORCID 0000-0001-9667-8438
The University of Texas Health Science Center at San Antonio · USInstituto Tecnológico de Costa Rica · CR
Funding
TRANSGENIC COREP30AG013319 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JAMES FLOYD NELSON · 1995 to 2026
$30.6M
South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Sudha Seshadri · 2021 to 2026
$24.0M
San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon, Elena Volpi · 2015 to 2026
$14.1M
Sulfatide deficiency: A novel mechanism leading to reactive astrogliosis in aging and Alzheimer’s diseaseRF1AG061729 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HAN, XIANLIN · 2021 to 2021
$1.9M
UTHealth-LINK- A PREP programR25GM130437 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HOPP, SARAH CHRISTINE, OYAJOBI, BABATUNDE OLUKAYODE · 2020 to 2024
$1.6M
Sulfatide deficiency: A novel mechanism leading to reactive astrogliosis in aging and Alzheimer’s diseaseR01AG061729 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HAN, XIANLIN · 2024 to 2025
$1.3M
Dysregulated intracellular calcium in microglia during Alzheimer's diseaseK01AG066747 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HOPP, SARAH CHRISTINE · 2020 to 2024
$547k
Sulfatide deficiency: A novel mechanism leading to reactive astrogliosis in aging and Alzheimer’s diseaseR56AG061729 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HAN, XIANLIN · 2019 to 2019
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain. · full record | Socratic