Evidence map›Paper›PMID 38113113›Full record

ArticleThe Journal of clinical investigation2023

Noncoding SNPs decrease expression of FABP5 during COPD exacerbations.

Manale El Kharbili, Sarah K Sasse, Lynn Sanford, Sean Jacobson, Katja Aviszus, Arnav Gupta, Claire Guo, Susan M Majka, Robin D Dowell, Anthony N Gerber and 2 more

Open access · goldAbstract read
In one paragraph

Article in The Journal of clinical investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Functional Variant Discovery Identifies a Novel Genetic Link between SPRY2, Wood Smoke, and Asthma.American journal of respiratory cell and molecular biology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Manale El KharbiliDepartment of Immunology and Genomic Medicine and.
Sarah K SasseDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Lynn SanfordBioFrontiers Institute.
Sean JacobsonDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Katja AviszusDepartment of Immunology and Genomic Medicine and.
Arnav GuptaDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Claire GuoDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Susan M MajkaDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Robin D DowellBioFrontiers Institute.
Anthony N GerberDepartment of Immunology and Genomic Medicine and.
Russell P BowlerDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Fabienne GallyDepartment of Immunology and Genomic Medicine and.
National Jewish Health · USInfrafrontier · DEUniversity of Colorado Boulder · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Mesenchymal Vascular Progenitor Depletion Promotes Lung Aging and Susceptibility to EmphysemaR35HL161238 · NHLBI · NATIONAL JEWISH HEALTH · PI SUSAN M MAJKA · 2022 to 2026
$4.9M
Role of FABP5 in COPD ExacerbationsR01HL141264 · NHLBI · NATIONAL JEWISH HEALTH · PI Fabienne Gally · 2019 to 2026
$3.7M
Loss of progenitor function accelerates lung agingR01AG073317 · NIA · NATIONAL JEWISH HEALTH · PI SUSAN M MAJKA, Richard Lee Reinhardt · 2023 to 2026
$2.7M
Loss of progenitor function accelerates lung agingR56AG073317 · NIA · NATIONAL JEWISH HEALTH · PI MAJKA, SUSAN M, REINHARDT, RICHARD LEE · 2021 to 2021
$336k
NHLBI NIH HHS R01 HL141264NHLBI NIH HHS R35 HL161238NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIA NIH HHS R01 AG073317
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotidePulmonary Disease, Chronic ObstructiveDisease ProgressionFatty Acid-Binding ProteinsHumansRisk FactorsFABP5 protein, humanFatty Acid-Binding ProteinsCOPDGeneticsMetabolism

Identifiers

PMID38113113
PMCPMC10849757
OpenAlexW4389979331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.