Evidence map›Paper›PMID 38124254›Full record

ArticleAge and ageing2023

The role of multimorbidity and socio-economic characteristics as potential risk factors for Long Covid: evidence from the multilevel analysis of the Survey of Health, Ageing and Retirement in Europe's corona surveys (2020-2021).

Piotr Wilk, Valerie Moran, Maria N Pi Alperin, Torsten Bohn, Guy Fagherazzi, Maurice P Zeegers, Maria Ruiz-Castell

Open access · hybridAbstract read
In one paragraph

Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence.Archives of public health = Archives belges de sante publique · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Piotr WilkDepartment of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Canada.
Valerie MoranDepartment of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Maria N Pi AlperinLiving Conditions Department, Luxembourg Institute of Socio-Economic Research, Esch-sur-Alzette, Luxembourg.
Torsten BohnDepartment of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.ORCID 0000-0002-7825-0697
Guy FagherazziDepartment of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Maurice P ZeegersDepartment of Epidemiology, Maastricht University, Maastricht, the Netherlands.
Maria Ruiz-CastellDepartment of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Luxembourg Institute of Health · LULuxembourg Institute of Socio-Economic Research · LUMaastricht University · NLWestern University · CA

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI KOSALI ILAYPERUMA SIMON · 1986 to 2026
$56.5M
WEALTH DISPARITIES AMONG MATURE AND OLDER ADULTSP01AG008291 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1989 to 2018
$19.4M
Enhancing the Comparability of SHARE with HRS and ELSAR01AG052527 · NIA · MAX PLANCK INST/SOCIAL LAW/SOCIAL POLICY · PI BOERSCH-SUPAN, AXEL H · 2016 to 2020
$2.1M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
Gene-by-Environment Interactions, Social Stress, and Depression in Older AdultsR03AG045301 · NIA · UNIVERSITY OF COLORADO · PI WHISMAN, MARK A · 2013 to 2013
$76k
RAND CENTER FOR THE STUDY OF AGINGP20AG012815 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1994 to 1999
–
NIA NIH HHS HHSN271201300071CNIA NIH HHS P01 AG005842NIA NIH HHS P01 AG008291NIA NIH HHS P20 AG012815NIA NIH HHS R01 AG052527NIA NIH HHS R03 AG045301NIA NIH HHS R21 AG025169NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

backgroundA substantial proportion of individuals continue experiencing persistent symptoms following the acute stage of their Covid-19 illness. However, there is a shortage of population-based studies on Long Covid risk factors.

objectiveTo estimate the prevalence of Long Covid in the population of middle-aged and older Europeans having contracted Covid-19 and to assess the role of multimorbidity and socio-economic characteristics as potential risk factors of Long Covid.

methodsA population-based longitudinal prospective study involving a sample of respondents 50 years and older (n = 4,004) from 27 countries who participated in the 2020 and 2021 Survey of Health, Ageing and Retirement in Europe (SHARE), in particular the Corona Surveys. Analyses were conducted by a multilevel (random intercept) hurdle negative binomial model.

resultsOverall, 71.6% (95% confidence interval = 70.2-73.0%) of the individuals who contracted Covid-19 had at least one symptom of Long Covid up to 12 months after the infection, with an average of 3.06 (standard deviation = 1.88) symptoms. There were significant cross-country differences in the prevalence of Long Covid and number of symptoms. Higher education and being a man were associated with a lower risk of Long Covid, whilst being employed was associated with a higher risk of having Long Covid. Multimorbidity was associated with a higher number of symptoms and older age was associated with a lower number of symptoms.

conclusionOur results provide evidence on the substantial burden of Long Covid in Europe. Individuals who contracted Covid-19 may require long-term support or further medical intervention, putting additional pressure on national health care systems.

Indexed as

Post-Acute COVID-19 SyndromeAgedAge FactorsEuropeHumansMaleMiddle AgedMultilevel AnalysisMultimorbidityProspective StudiesRisk FactorsSocioeconomic FactorsSurveys and QuestionnairesAgeing and Retirement in Europe (SHARE)Long Covidmultilevel modelmultimorbidityolder peoplesocio-economic factorsSurvey of Health

Identifiers

PMID38124254
PMCPMC10733586
OpenAlexW4390063192

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.