ArticleBiofabrication2024
A vascularized 3D model of the human pancreatic islet for
Open access · hybridAbstract read
In one paragraph
Article in Biofabrication, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Applications of Stem Cell-Derived Islets and Emerging Experimental Platforms to Understand Diabetes.Diabetes · 2026Review
- A microphysiological system HHT-on-a-chip platform recapitulates patient vascular lesions.Nature communications · 2026Article
- Engineering etiology-aligned in vitro models of human vessels.Microsystems & nanoengineering · 2026Review
- Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs-On-Chips.Advanced biology · 2026Review
- The Role of Gene Therapy and RNA-Based Therapeutic Strategies in Diabetes.International journal of molecular sciences · 2025Review
- Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids.Developmental cell · 2025Article
- Progress in recapitulating morphogenesis of blood microvascular structures for microphysiological systems development.Biochemical Society transactions · 2025Article
- Closing the Gap Between Vision and Victory in Type 1 Diabetes: The NIDDK Human Islet Research Network (HIRN) Initiative.Diabetes · 2025Review
- Oxygen dynamics and delivery strategies to enhance beta cell replacement therapy.American journal of physiology. Cell physiology · 2025Review
- Vascularization of human islets by adaptable endothelium for durable and functional subcutaneous engraftment.Science advances · 2025Article
- Impact of vascular density on pancreatic islet viability: a computational study.Frontiers in physiology · 2025Article
- Methods for processing and analyzing images of vascularized micro-organ and tumor systems.Frontiers in bioengineering and biotechnology · 2025Article
- Bioengineering vascularization.Development (Cambridge, England) · 2024Review
- Identification of unique cell type responses in pancreatic islets to stress.Nature communications · 2024Article
- Capturing physiological hemodynamic flow and mechanosensitive cell signaling in vessel-on-a-chip platforms.Frontiers in physiology · 2024Review
- Advances in the Model Structure of In Vitro Vascularized Organ-on-a-Chip.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- 3D multicellular systems in disease modelling: From organoids to organ-on-chip.Frontiers in cell and developmental biology · 2023Review
- Using single-cell multi-omics screening of human fetal pancreas to identify novel players in human beta cell development.Diabetic medicine : a journal of the British Diabetic Association · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 2 countries.
R Hugh F BenderDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Benjamen T O'DonnellDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.ORCID 0000-0002-3529-231X
Bhupinder ShergillDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.
Brittany Q PhamDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Sima TahmouresieDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Celeste N SanchezDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Damie J JuatDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Michaela M S HatchDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
Venktesh S ShirureDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.
Matthew WorthamPediatric Diabetes Research Center, Department of Pediatrics, University of California, San Diego, CA, United States of America.
Kim-Vy Nguyen-NgocPediatric Diabetes Research Center, Department of Pediatrics, University of California, San Diego, CA, United States of America.
Yesl JunPediatric Diabetes Research Center, Department of Pediatrics, University of California, San Diego, CA, United States of America.
Roberto GaetaniDepartment of Bioengineering, University of California, San Diego, CA, United States of America.
Karen L ChristmanDepartment of Cellular & Molecular Medicine, University of California, San Diego, CA, United States of America.
Luc TeytonDepartment of Immunology & Microbiology, The Scripps Research Institute, San Diego, CA, United States of America.
Steven C GeorgeDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.
Maike SanderPediatric Diabetes Research Center, Department of Pediatrics, University of California, San Diego, CA, United States of America.
Christopher C W HughesDepartment of Molecular Biology & Biochemistry, University of California, Irvine, CA, United States of America.
University of California, Irvine · USUniversity of California San Diego · USUniversity of California, Davis · USScripps Research Institute · US
Funding
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4MThe Human Islet Distribution Coordinating Center (UC4)UC4DK098085 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI EVANS-MOLINA, CARMELLA, NILAND, JOYCE CAROL · 2012 to 2017
$25.6MIntegrated Islet Distribution Program (U24) - 2021U24DK098085 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Carmella Evans-Molina, Joyce Carol Niland · 2021 to 2026
$17.8MNIDDK NIH HHS P30 DK063491NIDDK NIH HHS UC4 DK098085
Abstract
Insulin is an essential regulator of blood glucose homeostasis that is produced exclusively by
Indexed as
Diabetes MellitusIslets of LangerhansIslets of Langerhans TransplantationGlucoseHumansInsulinGlucoseInsulindiabetesglucose-stimulated insulin secretionislet biologymicrophysiological systemsorgan-on-a-chip
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.