Evidence map›Paper›PMID 38129833›Full record

ReviewJournal of translational medicine2023

From cells to organs: progress and potential in cartilaginous organoids research.

Xiao-He Wang, Ning Liu, Hui Zhang, Zong-Sheng Yin, Zhen-Gang Zha

Open access · goldAbstract readReview
In one paragraph

Review in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  6. Association Between Chinese Visceral Adiposity Index and Risk of Incident Hypertension Among Older Adults: A Prospective Cohort Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiao-He WangDepartment of Bone and Joint Surgery, the First Affliated Hospital, Jinan University, Guangzhou, 510630, Guangdong, China.
Ning LiuDepartment of Bone and Joint Surgery, the First Affliated Hospital, Jinan University, Guangzhou, 510630, Guangdong, China.
Hui ZhangDepartment of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, Anhui, China.
Zong-Sheng YinDepartment of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, Anhui, China.
Zhen-Gang ZhaDepartment of Bone and Joint Surgery, the First Affliated Hospital, Jinan University, Guangzhou, 510630, Guangdong, China. wxhtgy@126.com.ORCID 0000-0001-8582-441X
First Affiliated Hospital of Jinan University · CNAnhui Medical University · CN

Funding

National Key R&D Program of China 2018YFC2002500National Natural Science Foundation of China 81602360National Natural Science Foundation of China 82072470Natural Science Foundation of Guangdong Province 2017A030313665Natural Science Foundation of Guangdong Province 2018A030313544Natural Science Foundation of Guangdong Province 2019A1515011082Natural Science Foundation of Guangdong Province 2020B1515120038Natural Science Foundation of Guangdong Province 2021A1515012154
6 · The paper itself

Abstract

While cartilage tissue engineering has significantly improved the speed and quality of cartilage regeneration, the underlying metabolic mechanisms are complex, making research in this area lengthy and challenging. In the past decade, organoids have evolved rapidly as valuable research tools. Methods to create these advanced human cell models range from simple tissue culture techniques to complex bioengineering approaches. Cartilaginous organoids in part mimic the microphysiology of human cartilage and fill a gap in high-fidelity cartilage disease models to a certain extent. They hold great promise to elucidate the pathogenic mechanism of a diversity of cartilage diseases and prove crucial in the development of new drugs. This review will focus on the research progress of cartilaginous organoids and propose strategies for cartilaginous organoid construction, study directions, and future perspectives.

Indexed as

OrganoidsTissue EngineeringBioengineeringCartilageHumansCartilageOrganoidsPluripotent stem cellsSpheroidsTissue engineering

Identifiers

PMID38129833
PMCPMC10740223
OpenAlexW4390059684

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.