Evidence map›Paper›PMID 38130480›Full record

ArticleACG case reports journal2023

Corydalis and Drug-Induced Liver Injury: A Series of 2 Cases.

Samuel Engman, Frances Puello, Kevin Khoury, Dustin Michael Miller, Kadir Isidan, Dhiren Shah

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Potential of isoquinoline-alkaloid-richFrontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel EngmanDepartment of Internal Medicine, Northshore University Health System, Chicago, IL.
Frances PuelloDepartment of Gastroenterology, Northshore University Health System, Chicago, IL.
Kevin KhouryDepartment of Gastroenterology, Northshore University Health System, Chicago, IL.
Dustin Michael MillerDepartment of Pathology, Des Moines University, Des Moines, IA.
Kadir IsidanDepartment of Pathology, Northshore University Health System, Chicago, IL.
Dhiren ShahDepartment of Gastroenterology, Northshore University Health System, Chicago, IL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corydalis is an herbal plant found in Asian countries. Research has demonstrated multiple health benefits. It has also been implicated in drug-induced liver injury. Cannabis dispensaries market a sleep aid which has corydalis as an active ingredient. We present 2 cases of corydalis-induced hepatotoxicity. An asymptomatic female patient exhibited a rise and fall of her transaminases coinciding with the consumption and rechallenge of this sleep aid. A man with symptoms consistent with liver dysfunction began taking the same sleep aid. With discontinuance, his liver function returned to normal. These 2 clinical cases provide evidence for corydalis-induced liver injury.

Indexed as

corydalisdrug-induced liver injuryhepatotoxicity

Identifiers

PMID38130480
PMCPMC10735149

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.