Evidence map›Paper›PMID 38137170›Full record

ReviewBrain sciences2023

Auditory Steady-State Responses in Schizophrenia: An Updated Meta-Analysis.

Inès Zouaoui, Alexandre Dumais, Marc E Lavoie, Stéphane Potvin

Open access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Abnormal spontaneous activity and rest-task shift in schizophrenia.Psychiatry and clinical neurosciences · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Inès ZouaouiCentre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal, Montreal, QC H1N 3V2, Canada.ORCID 0000-0002-6190-7154
Alexandre DumaisCentre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal, Montreal, QC H1N 3V2, Canada.ORCID 0000-0002-4480-0064
Marc E LavoieCentre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal, Montreal, QC H1N 3V2, Canada.ORCID 0000-0002-3037-3890
Stéphane PotvinCentre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal, Montreal, QC H1N 3V2, Canada.ORCID 0000-0003-1624-378X
Institut Universitaire en Santé Mentale de Québec · CAInstitut national de psychiatrie légale Philippe-Pinel · CAUniversité TÉLUQ · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis investigates auditory steady-state responses (ASSRs) as potential biomarkers of schizophrenia, focusing on previously unexplored clinical populations, frequencies, and variables. We examined 37 studies, encompassing a diverse cohort of 1788 patients with schizophrenia, including 208 patients with first-episode psychosis, 281 at-risk individuals, and 1603 healthy controls. The results indicate moderate reductions in 40 Hz ASSRs in schizophrenia patients, with significantly greater reductions in first-episode psychosis patients and minimal changes in at-risk individuals. These results call into question the expected progression of ASSR alterations across all stages of schizophrenia. The analysis also revealed the sensitivity of ASSR alterations at 40 Hz to various factors, including stimulus type, level of analysis, and attentional focus. In conclusion, our research highlights ASSRs, particularly at 40 Hz, as potential biomarkers of schizophrenia, revealing varied implications across different stages of the disorder. This study enriches our understanding of ASSRs in schizophrenia, highlighting their potential diagnostic and therapeutic relevance, particularly in the early stages of the disease.

Indexed as

ASSRelectroencephalographygamma rhythmmagnetoencephalographymeta-analysisschizophrenia

Identifiers

PMID38137170
PMCPMC10741772
OpenAlexW4389916196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.