Evidence map›Paper›PMID 38139224›Full record

ArticleInternational journal of molecular sciences2023

Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against

Bruna Gioia, Francesca Ruggieri, Alexandre Biela, Valérie Landry, Pascal Roussel, Catherine Piveteau, Florence Leroux, Ruben C Hartkoorn, Nicolas Willand

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruna GioiaUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.
Francesca RuggieriUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.
Alexandre BielaUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.ORCID 0000-0001-5749-3262
Valérie LandryUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.
Pascal RousselUniv. Lille, CNRS, ENSCL, Centrale Lille, Univ. Artois, UMR 8181-UCCS-Unité de Catalyse et de Chimie du Solide, F-59000 Lille, France.ORCID 0000-0001-7243-7293
Catherine PiveteauUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.
Florence LerouxUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.ORCID 0000-0003-0554-873X
Ruben C HartkoornUniv. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 8204-CIIL-Center for Infection and Immunity of Lille, F-59000 Lille, France.ORCID 0000-0001-7315-1553
Nicolas WillandUniv. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecules for Living Systems, F-59000 Lille, France.ORCID 0000-0002-0784-0462

Funding

Agence Nationale de la Recherche ANR-20-PAMR-0005European Union 847568
6 · The paper itself

Abstract

Historically, natural products have played a major role in the development of antibiotics. Their complex chemical structures and high polarity give them advantages in the drug discovery process. In the broad range of natural products, sesquiterpene lactones are interesting compounds because of their diverse biological activities, their high-polarity, and sp

Indexed as

Mycobacterium tuberculosisSesquiterpenesAnti-Inflammatory AgentsLactonesAnti-Inflammatory AgentsLactonesparthenolideSesquiterpenesMycobacterium tuberculosisnatural productssemisynthesis

Identifiers

PMID38139224
PMCPMC10744032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.