MD Simulations to Calculate NMR Relaxation Parameters of Vanadium(IV) Complexes: A Promising Diagnostic Tool for Cancer and Alzheimer's Disease.

Rodrigo Mancini Santos, Camila Assis Tavares, Taináh Martins Resende Santos, Hassan Rasouli, Teodorico Castro Ramalho

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Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 84% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Rodrigo Mancini SantosLaboratory of Molecular Modelling, Department of Chemistry, Federal University of Lavras, Lavras 37200-000, MG, Brazil.

Camila Assis TavaresLaboratory of Molecular Modelling, Department of Chemistry, Federal University of Lavras, Lavras 37200-000, MG, Brazil.ORCID 0000-0002-0710-3956

Taináh Martins Resende SantosLaboratory of Molecular Modelling, Department of Chemistry, Federal University of Lavras, Lavras 37200-000, MG, Brazil.

Hassan RasouliLaboratory of Molecular Modelling, Department of Chemistry, Federal University of Lavras, Lavras 37200-000, MG, Brazil.ORCID 0000-0002-1269-1617

Teodorico Castro RamalhoLaboratory of Molecular Modelling, Department of Chemistry, Federal University of Lavras, Lavras 37200-000, MG, Brazil.ORCID 0000-0002-7324-1353

Universidade Federal de Lavras · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early phase diagnosis of human diseases has still been a challenge in the medicinal field, and one of the efficient non-invasive techniques that is vastly used for this purpose is magnetic resonance imaging (MRI). MRI is able to detect a wide range of diseases and conditions, including nervous system disorders and cancer, and uses the principles of NMR relaxation to generate detailed internal images of the body. For such investigation, different metal complexes have been studied as potential MRI contrast agents. With this in mind, this work aims to investigate two systems containing the vanadium complexes [VO(metf)

Indexed as

computational chemistrymolecular dynamicsNMR relaxationOWSCAvanadium complexes

Identifiers

PMID38139780

DOI10.3390/ph16121653

PMCPMC10747690

OpenAlexW4389045166

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.