Evidence map›Paper›PMID 38142273›Full record

ReviewBiomaterials research2023

3D printed scaffolds based on hyaluronic acid bioinks for tissue engineering: a review.

Han Chen, Huaqian Xue, Huanxuan Zeng, Minghai Dai, Chengxuan Tang, Liangle Liu

Open access · goldAbstract readReview
PubMed Publisher
In one paragraph

Review in Biomaterials research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Hyaluronic Acid and Its Synthases-Current Knowledge.International journal of molecular sciences · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Han ChenThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Huaqian XueThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Huanxuan ZengThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Minghai DaiThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Chengxuan TangThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China. tangchengxuan@wmu.edu.cn.
Liangle LiuThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China. liuliangle@wmu.edu.cn.
Wenzhou Medical University · CNRuian People's Hospital · CN

Funding

Medical Science and Technology Project of Zhejiang Province No.2022KY354
6 · The paper itself

Abstract

Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique biological and physicochemical properties and ability to facilitate biological structure repair make it a promising candidate for three-dimensional (3D) bioprinting in the field of tissue regeneration and biomedical engineering. Moreover, HA is an ideal raw material for bioinks in tissue engineering because of its histocompatibility, non-immunogenicity, biodegradability, anti-inflammatory properties, anti-angiogenic properties, and modifiability. Tissue engineering is a multidisciplinary field focusing on in vitro reconstructions of mammalian tissues, such as cartilage tissue engineering, neural tissue engineering, skin tissue engineering, and other areas that require further clinical applications. In this review, we first describe the modification methods, cross-linking methods, and bioprinting strategies for HA and its derivatives as bioinks and then critically discuss the strengths, shortcomings, and feasibility of each method. Subsequently, we reviewed the practical clinical applications and outcomes of HA bioink in 3D bioprinting. Finally, we describe the challenges and opportunities in the development of HA bioink to provide further research references and insights.

Indexed as

3D printingBioinkBiomaterialHyaluronic acidTissue engineering

Identifiers

PMID38142273
OpenAlexW4390154765

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.