Evidence map›Paper›PMID 38146739›Full record

ArticleGlobal spine journal2024

Degenerative Thoracic Myelopathy: A Scoping Review of Epidemiology, Genetics, and Pathogenesis.

Tanzil Rujeedawa, Oliver D Mowforth, Benjamin M Davies, Cylene Yang, Aria Nouri, Jibin J Francis, Bizhan Aarabi, Brian K Kwon, James Harrop, Jefferson R Wilson and 5 more

Open access · goldAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 5 countries.

Tanzil RujeedawaDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7089-1684
Oliver D MowforthDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0001-6788-745X
Benjamin M DaviesDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0003-0591-5069
Cylene YangDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Aria NouriDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0002-4965-3059
Jibin J FrancisDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Bizhan AarabiUniversity of Maryland, Baltimore, MD, USA.
Brian K KwonVancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
James HarropThomas Jefferson University Hospital, Philadelphia, PA, USA.
Jefferson R WilsonUniversity of Toronto, Toronto, ON, Canada.ORCID 0000-0001-5965-0305
Allan R MartinDepartment of Neurosurgery, University of California Davis, Sacramento, CA, USA.
Vafa Rahimi-MovagharDepartment of Neurosurgery, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
James D GuestDepartment of Neurosurgery and The Miami Project to Cure Paralysis, The Miller School of Medicine, University of Miami, Miami, FL, USA.
Michael G FehlingsToronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5722-6364
Mark R KotterDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
University of Cambridge · GBSina Hospital · IRThomas Jefferson University Hospital · USUniversity Health Network · CAUniversity of British Columbia · CAUniversity of California, Davis · USUniversity of Maryland, Baltimore · USUniversity of Miami · USUniversity of Toronto · CA

Funding

Wellcome Trust
6 · The paper itself

Abstract

STUDY

designLiterature Review.

objectiveMyelopathy affecting the thoracic spinal cord can arise secondary to several aetiologies which have similar presentation and management. Consequently, there are many uncertainties in this area, including optimal terminology and definitions. Recent collaborative cervical spinal research has led to the proposal and subsequent community adoption of the name

methodsFollowing PRISMA guidelines, a systematic literature search was performed to identify degenerative thoracic myelopathy literature in Embase and MEDLINE.

resultsConditions encompassed within DTM include thoracic spondylotic myelopathy, ossification of the posterior longitudinal ligament, ossification of the ligamentum flavum, calcification of ligaments, hypertrophy of ligaments, degenerative disc disease, thoracic osteoarthritis, intervertebral disc herniation, and posterior osteophytosis. The classic presentation includes girdle pain, gait disturbance, leg weakness, sensory disturbance, and bladder or bowel dysfunction, often with associated back pain. Surgical management is typically favoured with post-surgical outcomes dependent on many factors, including the causative pathology, and presence of additional stenosis.

conclusionThe clinical entities encompassed by the term DTM are interrelated, can manifest concurrently, and present similarly. Building on the consensus adoption of

Indexed as

disc herniationmyelopathyossification of the posterior longitudinal ligamentspondylosisstenosisthoracic

Identifiers

PMID38146739
PMCPMC11394495
OpenAlexW4390231847

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.