Evidence map›Paper›PMID 38148113›Full record

ArticleLife science alliance2024

Extreme trait GWAS (Et-GWAS): Unraveling rare variants in the 3,000 rice genome.

Niranjani Gnanapragasam, Vinukonda Vishnu Prasanth, Krishna Tesman Sundaram, Ajay Kumar, Bandana Pahi, Anoop Gurjar, Challa Venkateshwarlu, Sanjay Kalia, Arvind Kumar, Shalabh Dixit and 4 more

Abstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Niranjani GnanapragasamInternational Rice Research Institute, South Asia Hub, Patancheru, India.ORCID 0000-0003-2795-742X
Vinukonda Vishnu PrasanthInternational Rice Research Institute, South Asia Hub, Patancheru, India.
Krishna Tesman SundaramInternational Rice Research Institute, South Asia Hub, Patancheru, India.
Ajay KumarInternational Rice Research Institute, South Asia Hub, Patancheru, India.
Bandana PahiInternational Rice Research Institute, South Asia Hub, Patancheru, India.
Anoop GurjarInternational Rice Research Institute, South-Asia Regional Centre, Varanasi, India.
Challa VenkateshwarluInternational Rice Research Institute, South Asia Hub, Patancheru, India.
Sanjay KaliaDepartment of Biotechnology, CGO Complex, New Delhi, India.
Arvind KumarInternational Rice Research Institute, South-Asia Regional Centre, Varanasi, India.
Shalabh DixitInternational Rice Research Institute, Los Banos, Philippines.
Ajay KohliInternational Rice Research Institute, Los Banos, Philippines.
Uma Maheshwer SinghInternational Rice Research Institute, South-Asia Regional Centre, Varanasi, India.
Vikas Kumar SinghInternational Rice Research Institute, South Asia Hub, Patancheru, India v.k.singh@irri.org.ORCID 0000-0002-1560-1648
Pallavi SinhaInternational Rice Research Institute, South Asia Hub, Patancheru, India p.sinha@irri.org.ORCID 0000-0003-0810-0711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying high-impact, rare genetic variants associated with specific traits is crucial for crop improvement. The 3,010 rice genome (3K RG) dataset offers a valuable resource for discovering genomic regions with potential applications in crop breeding. We used Extreme Trait GWAS (Et-GWAS), employing bulk pooling and allele frequency measurement to efficiently extract rare variants from the 3K RG. This innovative approach facilitates the detection of associations between genetic variants and target traits, concentrating and quantifying rare alleles. In our study, on grain yield under drought stress, Et-GWAS successfully identified five key genes (

Indexed as

OryzaGene FrequencyGenome-Wide Association StudyPhenotypeQuantitative Trait Loci

Identifiers

PMID38148113
PMCPMC10751245

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.