Evidence mapPaperPMID 38159807Full record

ArticleThe journal of allergy and clinical immunology. In practice2024

Weight Loss Interventions for Adults With Obesity-Related Asthma.

Dinah Foer, Erick Forno, Fernando Holguin, Katherine N Cahill

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Article
  5. Non-T2 asthma.Current opinion in pulmonary medicine · 2025
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Dinah FoerDivision of General Internal Medicine and Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Erick FornoDivision of Pulmonology, Allergy/Immunology, and Sleep Medicine, Department of Pediatrics, Indiana University School of Medicine and Riley Hospital for Children, Indianapolis, Ind.
Fernando HolguinDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, Colo.
Katherine N CahillDivision of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: Katherine.cahill@vumc.org.
Brigham and Women's Hospital · USRiley Hospital for Children · USUniversity of Colorado Anschutz Medical Campus · USVanderbilt University Medical Center · US

Funding

Glucagon-Like Peptide-1 Receptor Agonist Treatment in Adult, Obesity-Related, Symptomatic AsthmaU01AI155299 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$2.3M
SANDIA: Supplementing L-citrulline to overweight late Asthma oNset phenotypes to increase airway L-arginine/ADMA ratio and Improve Asthma controlR01HL146542 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Fernando Holguin, Loretta G Que · 2023 to 2023
$701k
Effects of GLP-1 Receptor Agonists on Airway Inflammation and Platelet Activation in AsthmaK23HL161332 · BRIGHAM AND WOMEN'S HOSPITAL · 2025 to 2025
$195k
NHLBI NIH HHS K23 HL161332NHLBI NIH HHS R01 HL146542NHLBI NIH HHS R01 HL149693NIAID NIH HHS U01 AI155299
6 · The paper itself

Abstract

Obesity is a common asthma comorbidity in adults, contributing to higher patient morbidity and mortality. Conversely, weight loss can reduce the impact of obesity on asthma and improve patient outcomes by diverse mechanisms including modulating airway inflammation, reducing oxidative stress, and improving lung function. Multiple lifestyle, nonpharmacological, pharmacological, and surgical interventions are effective at reducing weight in the general population. Fewer have been studied specifically in the context of patients with asthma. However, increasingly effective pharmacologic options for weight loss highlight the need for allergists and pulmonologists to understand the range of approaches that may directly or indirectly yield clinical benefits in asthma management. Weight loss interventions often require multidisciplinary support to create strategies that can realistically achieve a patient's personalized asthma and weight goals. This includes minimizing the adverse weight effects of glucocorticoids, which remain a mainstay of asthma management. Disparities in access, cost, and insurance coverage of weight loss interventions remain acute challenges for providers and patients. Future studies are needed to elucidate mechanisms of action of specific weight loss interventions on short-term and long-term asthma outcomes.

Indexed as

AsthmaObesityAdultComorbidityHumansLife StyleWeight LossBariatric surgeryBody mass indexDietDisparitiesExerciseGlucagon-like peptide-1

Identifiers

PMID38159807
PMCPMC10999349
OpenAlexW4390331614

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.